The significance of Choline for All Around Health

 

Choline: The Secret Nutrient?

Video taken from the channel: The Doctors


 

#46–Chris Masterjohn, Ph.D.: Pathways to health and disease (NAD, sirtuins, methylation, choline…

Video taken from the channel: PeterAttiaMD


 

What Choline Is And Why You Need It

Video taken from the channel: Bestie


 

The Importance of Choline for Health, Cognition, and Pregnancy

Video taken from the channel: Raqib Zaman


 

Choline Benefits for Brain Function and Libido

Video taken from the channel: Chad Howse


 

Brain Cognition And Choline

Video taken from the channel: MonkeySee


 

What is Choline & Why is it Important?

Video taken from the channel: Christine’s Mostly Keto Kitchen


 

Choline: The Secret Nutrient?

Video taken from the channel: The Doctors


 

Choline Benefits for Brain Function and Libido

Video taken from the channel: Chad Howse


 

#46–Chris Masterjohn, Ph.D.: Pathways to health and disease (NAD, sirtuins, methylation, choline…

Video taken from the channel: PeterAttiaMD


 

The Importance of Choline for Health, Cognition, and Pregnancy

Video taken from the channel: Raqib Zaman


 

What Choline Is And Why You Need It

Video taken from the channel: Bestie


 

Brain Cognition And Choline

Video taken from the channel: MonkeySee


 

What is Choline & Why is it Important?

Video taken from the channel: Christine’s Mostly Keto Kitchen


The Importance of Choline for Overall Health Choline Recommended Dosages and Use. The recommended dosage of choline depends on your age, gender, and whether you’re Forms of Choline. The three most popular forms of orally ingested choline are. Impact on Your Brain Memory and Brain Function. Brain Development.

Several animal studies suggest that taking choline supplements during pregnancy may improve fetal Mental Health. Some evidence suggests choline may play a role in the development and. Choline has been shown to boost brain health as you age, and may prevent certain forms of cognitive decline. In addition to fetal and infant brain development, choline is important to cognitive function later in life, as well.

Doctors have long been recommending choline as the body ages, to keep memory intact. As people continue to live longer and the mind declines, the. The importance of ensuring adequate choline intakes during pregnancy is increasingly recognized. Choline is critical for a number of physiological processes during the prenatal period with roles in membrane biosynthesis and tissue expansion, neurotransmission and brain development, and methyl group donation and gene expression.

In addition, choline is needed to produce acetylcholine, an important neurotransmitter for memory, mood, muscle control, and other brain and nervous system functions [ 1-3 ]. Choline also plays important roles in modulating gene expression, cell membrane signaling, lipid transport and metabolism, and early brain development [ 1, 2 ]. Choline is a macronutrient that’s important for liver function, normal brain development, nerve function, muscle movement, supporting energy levels and maintaining a healthy metabolism. Nutritional Importance of Choline Choline is an essential nutrient for humans and is necessary for the normal function of all cells. As a critical component of the cell membrane, it ensures the structural integrity and signaling functions of the cell. Choline is the head-group of phosphatidylcholines – an essential human nutrient – as it holds a wide range of roles in the human metabolism.

It is a vitamin-like nutrient crucial for normal cellular function. Many organs such as the brain, liver, kidney, pancreas and muscles all depend on an adequate choline intake. Choline is a nutrient that is found in many foods. Your brain and nervous system need it to regulate memory, mood, muscle control, and other functions.

You also need choline to form the membranes that surround your body’s cells.

List of related literature:

The importance of choline as a nutrient was first appreciated during early research on the functions of insulin (7,8) when it was found to be the nutrient needed to prevent fatty liver and death in dogs lacking a pancreas.

“Handbook of Vitamins” by Robert B. Rucker, John W. Suttie, Donald B. McCormick
from Handbook of Vitamins
by Robert B. Rucker, John W. Suttie, Donald B. McCormick
CRC Press, 2001

A dietary requirement for choline was definitively demonstrated in healthy men participating in a choline depletion–repletion metabolic study (Zeisel et al., 1991), the results of which guided the establishment of choline adequate intake levels in 1998 (IOM, 1998).

“Biochemical, Physiological, and Molecular Aspects of Human Nutrition E-Book” by Martha H. Stipanuk, Marie A. Caudill
from Biochemical, Physiological, and Molecular Aspects of Human Nutrition E-Book
by Martha H. Stipanuk, Marie A. Caudill
Elsevier Health Sciences, 2018

Nutritional importance of choline for brain development.

“Herbs and Natural Supplements Inkling: An Evidence-Based Guide” by Lesley Braun, Marc Cohen
from Herbs and Natural Supplements Inkling: An Evidence-Based Guide
by Lesley Braun, Marc Cohen
Elsevier Health Sciences APAC, 2010

Further discussions on the role of choline for critical biological functions and health outcomes are found later in this chapter.

“Present Knowledge in Nutrition” by John W. Erdman, Jr., Ian A. MacDonald, Steven H. Zeisel
from Present Knowledge in Nutrition
by John W. Erdman, Jr., Ian A. MacDonald, Steven H. Zeisel
Wiley, 2012

Whether dietary or supplemental choline is beneficial or harmful to humans has not been determined (Leermakers et al. 2015), but as claim goes, the benefits include reducing the risk of neural tube defects and fatty liver disease.

“Therapeutic Use of Medicinal Plants and their Extracts: Volume 2: Phytochemistry and Bioactive Compounds” by A.N.M. Alamgir
from Therapeutic Use of Medicinal Plants and their Extracts: Volume 2: Phytochemistry and Bioactive Compounds
by A.N.M. Alamgir
Springer International Publishing, 2018

In mammalian species, but not avians, excess dietary Met can eliminate the dietary need for preformed choline (17, 18, 36, 37), and betaine, which is also present in many foods and feeds (38), can replace the methylation function of choline (31).

“From Research to Manuscript: A Guide to Scientific Writing” by Michael Jay Katz
from From Research to Manuscript: A Guide to Scientific Writing
by Michael Jay Katz
Springer Netherlands, 2009

Choline helps reduce levels of homocysteine, a harmful amino acid that has been correlated with heart disease, and is a building block for acetylcholine, the neurotransmitter responsible for memory and mood.

“The Rainbow Diet: A Holistic Approach to Radiant Health Through Foods and Supplements” by Deanna Minich
from The Rainbow Diet: A Holistic Approach to Radiant Health Through Foods and Supplements
by Deanna Minich
Mango Media, 2018

Choline is an essential dietary component that ensures the structural integrity and signaling functions of the cell membranes; it is a major source of methyl groups in the diet, and it directly affects cholinergic neurotransmission, transmembrane signaling, and lipid transport and metabolism.

“Healing Lyme Disease Coinfections: Complementary and Holistic Treatments for Bartonella and Mycoplasma” by Stephen Harrod Buhner
from Healing Lyme Disease Coinfections: Complementary and Holistic Treatments for Bartonella and Mycoplasma
by Stephen Harrod Buhner
Inner Traditions/Bear, 2013

Health outcomes associated with choline involve memory, heart disease, and inflammation, which also explain the consideration of choline as a plausible intervention in traumatic brain injury (TBI).

“Nutrition and Traumatic Brain Injury: Improving Acute and Subacute Health Outcomes in Military Personnel” by Institute of Medicine, Food and Nutrition Board, Committee on Nutrition, Trauma, and the Brain, Laura Pillsbury, Maria Oria, John Erdman
from Nutrition and Traumatic Brain Injury: Improving Acute and Subacute Health Outcomes in Military Personnel
by Institute of Medicine, Food and Nutrition Board, et. al.
National Academies Press, 2011

Choline helps the liver and gallbladder function and is vital to brain chemistry, as it seems to aid thinking capacity and memory.

“Principles of Orthomolecularism” by R. A. S. Hemat
from Principles of Orthomolecularism
by R. A. S. Hemat
Urotext, 2004

Alexia Lewis RD

Registered Dietitian Nutritionist and Certified Heath Coach who believes life is better with science, humor, and beautiful, delicious, healthy food.

[email protected]

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18 comments

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  • Thats an excellent study on pregnant women who took choline during their 2/3 trimesters showing their kids grew up to be smart in school.

  • Was this video helpful or informative for you? Are there any similar topics related to nutritional info that you’d like to see us tackle in the near future? If you enjoyed this video, please give it a like and share it with your friends! ��

  • Choline a super nutrient can improve brain cognition @The Choline Information Council  thttps:// http://www.youtube.com/watch?v=XiILbh4zME8

  • The video is overly optimistic about being able to meet the RDA for choline on a plant based diet alone. Animal sources of choline such as eggs carry significantly more choline than any plant source. You would need to eat more than 30 servings of broccoli to get the choline benefits of an egg. It’s probably true that vegans and vegetarians would require supplementation in order to get enough.

  • Very great video.
    All those Benefits are similar to CoQ10 Enzyme.
    Would be great if you can a video explaining the difference.
    Thanks a lot

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  • ofcours vitamin C, helps with colds, I take it when I have a cold and it helps my cold go away in as little as two days. its really good!!

  • Great to see all the Attia content uploaded onto YouTube and with the fantastic breakdown of content by time line. Thanks Peter, please persist with the channel and it will take off as big as the podcast!

  • How cow, goat and most of the grass eater get it? Specially Elephant?

    Whatever, choline is water soluble right? How can you find it is soybean oil?

  • Choline is needed in fat metabolism. This occurs in the liver. If there is a choline deficiency, the liver can become fatty, reducing its efficiency and eventually making someone gain weight. Also, someone who is already on a Keto/IF diet might not lose weight, or has weight loss stalled because of a choline deficiency. The liver needs this water-soluble co-factor in order to metabolize fat. It is the liver that metabolizes dietary fat into the correct fatty compounds the brain is made of, thus feeding the brain with the correct nutrients.

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  • Is there a reason people always consider niconamide, but never nicotinic acid (with carboxyl functionality) form of vitamin B3 when considering NAD boosters? Because when I take nicotinic acid, I can literally feel the flush in my peripheral vasculature, proving the nicotinic acid is bypassing the hepatic portal 1st pass metabolism because I can literally feel the flush (due to nicotinic acid) throughout my body?

    Is there something I’m missing or something I’m overlooking? I realize when nicotinic acid enters the cell, there are several enzymes needed to turn this nicotinic acid into NAD? Perhaps the regulation or kinetics of the enzymes involved in nicotinic acid -> NAD have negligibly small rate constants or have regulation that minimizes the flux of this pathway? I doubt the PRPP or ATP cofactors would be rate limiting assuming we’re in the fed state with glucose and insulin (and therefore PPP activation and sufficient ATP levels).

  • what about just taking choline bitartrate, i watched anohter vid saying that this kind is not as well absorbed, what is ur opinion and i have to say that the price for manbrain is up there

  • Very great video.
    All those Benefits are similar to CoQ10 Enzyme.
    Would be great if you can a video explaining the difference.
    Thanks a lot

  • what about just taking choline bitartrate, i watched anohter vid saying that this kind is not as well absorbed, what is ur opinion and i have to say that the price for manbrain is up there

  • How cow, goat and most of the grass eater get it? Specially Elephant?

    Whatever, choline is water soluble right? How can you find it is soybean oil?

  • Was this video helpful or informative for you? Are there any similar topics related to nutritional info that you’d like to see us tackle in the near future? If you enjoyed this video, please give it a like and share it with your friends! ��

  • The fact that 92% of the population is deficient in this powerful compound is insane. The cognitive benefits of choline are what interest me most, which is also why I made Man Brain for my folks. You don’t ‘have to’ supplement with much, but choline seems to be up there in the things that are close to necessary to supplement with.