The Fir Technique to get the most from Your Protein

 

A Closer Look at…Parkinson’s Disease

Video taken from the channel: University of California Television (UCTV)


 

Calories vs Macros & What To Focus On For YOUR Goals FREE Fat Loss Guide

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New Frontiers in Targeted Protein Degradation and Degrader Development

Video taken from the channel: R&D Systems, a Bio-Techne brand


 

Is Herd-Immunity Achieved In Some Places? Sweden Reloaded

Video taken from the channel: Drbeen Medical Lectures


 

Britt Glaunsinger (UCB, HHMI) 1: Viruses Reveal the Secrets of Biology

Video taken from the channel: iBiology


 

Deshaies (Amgen) 1: A primer on the ubiquitin-proteasome system

Video taken from the channel: iBiology


 

Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

Video taken from the channel: FoundMyFitness


If your goal is to boost muscle recovery and size, it’s a good strategy to spread out protein intake and sandwich protein-containing foods around your workout. What this looks like: Divide your protein up into three meals and two snacks per day. 2. Snack on Cheese. Snacks are a good way to get extra protein into your diet, as long as you choose the right types.

Many common snack foods are very low in. In addition, von Moger also recommends that you drink a casein protein shake before bed, shooting for 20-40 grams of casein. Even while asleep, your body utilizes some protein overnight, so it’s important to keep your levels of this critical nutrient high. They often want to gain weight and require more protein and calories. A protein + carbohydrate (P+C) drink during training can help here too.

Fitness competitors usually accumulate a lot of exercise hours trying to drop to a single-digit body fat percentage. To accomplish this, carb and calorie intake should be. 5. Lastly, a strategy that I think is the most important when starting out, is to put your at least 2/3 of your meals in the night before into myfitnesspal so there is no guessing the next day on what you are going to eat.

This will ensure that you are not sitting there at 8pm with 80g protein and minimal carbs and fats left. Drink a cup of skim milk, and you’ll add 8 grams of protein to your daily total. Or up your game with a carton of fat-free Greek yogurt, with up to 20 grams.

Three daily servings of fat-free or. Therefore, an ideal protein purification strategy is one in which the highest level of purification is reached in the fewest steps. The selection of which steps to use is dependent on the size, charge, solubility and other properties of the target protein. The following techniques are most appropriate for purifying a single cytosolic protein. grains and dairy. grilled cheese on whole wheat bread.

It was previously believed that vegetarian proteins must be consumed at the same meal in order for the body to form complete proteins. Now it. Increase your protein intake. You should aim eat between 1 and 1.2 grams per pound of lean mass throughout pregnancy and breastfeeding.

Use our keto calculator and body fat percentage estimation guide to help you figure out the right amount of protein for you. Up your carb and fat intake later in pregnancy. Later in the pregnancy and while breastfeeding, add in 30-50g of extra carbs from. Beans and Peas.

Beans are the most commonly talked about protein-rich plant-based alternative. At about 39 grams of protein per cup, black beans are one of the most protein-dense foods you can eat that is free of animal products. For comparison’s sake, a cup of chopped or diced chicken breast has 43 grams of protein.

List of related literature:

Either shifting the diet composition to a lower percentage of protein (scenario 1), or effectively doing the same by having low levels of energy expenditure (scenario 4), will result in overconsumption of energy to maintain protein intake.

“The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity” by Stephen J. Simpson, David Raubenheimer
from The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity
by Stephen J. Simpson, David Raubenheimer
Princeton University Press, 2012

Therefore, combining proteins at each meal is not necessary, and by consuming a variety of plant sources such as whole grains, nuts, seeds, legumes and vegetables throughout the day, an adequate intake of essential amino acids should be achieved.

“Midwifery: Preparation for Practice” by Sally Pairman, Sally K. Tracy, Carol Thorogood, Jan Pincombe
from Midwifery: Preparation for Practice
by Sally Pairman, Sally K. Tracy, et. al.
Elsevier Health Sciences, 2011

Combining a modest supply of protein as amino acids (6 to 12 g essential amino acids) with a carbohydrate source (20 to 40 g) after exercise may result in even greater increases in protein synthesis.

“NSCA’s Guide to Sport and Exercise Nutrition” by NSCA -National Strength & Conditioning Association, Bill Campbell, Marie Spano
from NSCA’s Guide to Sport and Exercise Nutrition
by NSCA -National Strength & Conditioning Association, Bill Campbell, Marie Spano
Human Kinetics, Incorporated, 2011

Consuming this even protein distribution with 30g of protein at each meal stimulates 24-h muscle protein synthesis more effectively than an uneven protein distribution (Mamerow et al., 2014).

“Advances in Food and Nutrition Research” by Fidel Toldra
from Advances in Food and Nutrition Research
by Fidel Toldra
Elsevier Science & Technology, 2020

To prepare for a contest, a competitor must consume adequate amounts of all amino acids; therefore, vegetarians must mix complementary protein sources to prevent deficiencies.

“Bodybuilding: The Complete Contest Preparation Handbook” by Peter J. Fitschen, Cliff Wilson
from Bodybuilding: The Complete Contest Preparation Handbook
by Peter J. Fitschen, Cliff Wilson
Human Kinetics, Incorporated, 2019

To ensure an adequate supply of protein in your diet, eat a small serving of protein at each meal and include a bit of protein (such as a few nuts or a small piece of cheese) with each snack, for a total of approximately 8 to 10 ounces of protein daily.

“User's Guide to Nutritional Supplements” by Jack Challem
from User’s Guide to Nutritional Supplements
by Jack Challem
Basic Health Publications, Incorporated, 2003

The goal should be to meet both the RDA for protein and the population-safe intake levels for essential amino acids.

“Biochemical, Physiological, and Molecular Aspects of Human Nutrition E-Book” by Martha H. Stipanuk, Marie A. Caudill
from Biochemical, Physiological, and Molecular Aspects of Human Nutrition E-Book
by Martha H. Stipanuk, Marie A. Caudill
Elsevier Health Sciences, 2018

“You need about 70 to 75 grams of protein a day, which is easier than you think, If you eat three servings of lean protein and at least four servings of milk or milk products, you’re two-thirds of the way there.

“The Pregnancy Countdown Book: Nine Months of Practical Tips, Useful Advice, and Uncensored Truths” by Susan Magee, Kara Nakisbendi
from The Pregnancy Countdown Book: Nine Months of Practical Tips, Useful Advice, and Uncensored Truths
by Susan Magee, Kara Nakisbendi
Quirk Books, 2006

Protein, particularly sources that are rich in the branched-chain amino acids (leucine, isoleucine, and valine), should be taken in at a carb-to-protein ratio of about 4:1 or 5:1 over the 30-minute recovery period.

“The Paleo Diet for Athletes: The Ancient Nutritional Formula for Peak Athletic Performance” by Loren Cordain, Joe Friel
from The Paleo Diet for Athletes: The Ancient Nutritional Formula for Peak Athletic Performance
by Loren Cordain, Joe Friel
Rodale Books, 2012

But the latter matters far more, especially since, as we’ve noted (see page 151), you do NOT need to depend on any one food for your protein; you can get it from any balanced variety of foods over the course of a typical day and week.

“How to Eat: All Your Food and Diet Questions Answered” by Mark Bittman, David Katz
from How to Eat: All Your Food and Diet Questions Answered
by Mark Bittman, David Katz
Houghton Mifflin Harcourt, 2020

NOAH BRYANT

Hardcore strength training is what I am about. I am a personal trainer, author, and contributor to lots of different lifting and fitness magazines.

I was a 2x NCAA champion in the shoutput at USC and I represented the USA at the 2007 World Championships as well as the 2011 PanAm Championships.

Contact me to find out more about my personalized online training and how I can help you reach your goals.

Education: Bachelor of Science (B.S.), Public Policy, Planning, And Development @ University of Southern California

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152 comments

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  • in her new book how to starve cancer jane maclland says autophagy can be a fuel for cancer and needs to be stopped as it acts as fuel for the cancer cell at certain  periods of the process. The cancer cell uses autophagy when arginine  is deprived it used glutimine

  • Only at 25:55 he got the first opportunity to get a glimpse at Rhonda’s legs AND HE TOOK IT! What a tough man he fought it half an hour ��

  • Thank you so much! So much time you must have spent putting all of this together. Pro tip:I watch this on my phone and tablet at the same time so I can pause the pictures and articles. Probably because I’m slow and need more autophagy in my life.

  • As usual when scientific info is dummed down through the media for mass population key facts are missed/misinterpreted. This benefits those who exploit this lack of understanding and sell books, do talks/videos etc for profit and promote themselves as ‘experts’ but few actually check their credentials or sources cited (if any).

  • Great topic, super interesting, trying my best to follow. Very advanced….Thank you for the stimulation….

    Whole plant based foods on Instagram = mikewakethefoodup

  • In Mississippi the cases started to go down, but that was because they reduced the number of tests by a third from July 15th to Auguat 15th.

  • Another excellent interview, Dr. Patrick. You maximized this opportunity! Thanks so much to both Docs, and soon I’ll be supporting at Patreon.

  • TIMELINE…
    00:03:22 How genetically inhibiting autophagy actually increases cellular sensitivity to death and how this was counterintuitive because autophagy was thought, at one time, as a type of activity predominantly concerned with actually initiating cell death.
    00:04:44 The external signals causing autophagy.
    00:05:29 The role of growth factors in transporting nutrients from the outside world into the intracellular space.
    00:05:48 Autophagy as a process that destroys bioenergetic macromolecular reserves including proteins, lipids, and nucleic acids to generate energy.
    00:06:28 How declines in the ATP (energetic) status of the cell trigger autophagy by increasing the activity of a pathway known as AMP Kinase.
    00:06:36 How reductions in the cytosolic pool of acetyl-CoA as a consequence of reductions in glycolysis, amino acid catabolism, or beta-oxidation, ultimately result in the de-acetylation of hundreds of cellular proteins involved in autophagy. Nutrient deprivation → ↑ Protein Deacetylation (↓ cytosolic Acetyl CoA) + ↓ mTOR + ↑ AMP Kinase → Autophagy
    00:09:37 The role of the inhibition of mTOR and activation of AMP Kinase in cellular autophagy. mTOR is a pathway robustly activated by IGF-1 and associated with increases in cell growth, proliferation, motility and protein synthesis. AMP Kinase, on the other hand, is a pathway important in regulating cellular energy homeostasis by inhibiting synthesis of fatty acids and triglycerides and activating fatty acid uptake and beta-oxidation in the liver.
    00:09:37 The indirect relationship between protein acetylation status (and cytosolic acetyl CoA availability) and the suppression of mTOR and activation of AMP Kinase in cellular autophagy.
    00:10:23 The possibility of using selective nutrient restriction as an autophagy-inducer instead of more generalized nutrient deprivation or fasting.
    00:11:11 Cytoplasmic protein deacetylation as a potential surrogate marker for fasting-induced autophagy (still undergoing validation) but possibly not other forms of autophagy, such as the kind pharmacologically induced by interaction with a protein involved in vesicle-trafficking processes called Beclin 1.
    00:12:53 How a protein called LC3 associate with structures called autophagosomes to facilitate autophagy in response to deacetylation it undergoes. Note: this sirt1-mediated deacetylation of LC3 is induced as an important response to cell starvation.
    00:14:22 The special flow cytometry needed in order to measure some of the proteins associated with the activation of autophagosomes in autophagy.
    00:15:04 The desirability of being able to know and test whether or not your fasting is triggering robust autophagy or not.
    00:16:30 The minimum amount of fasting necessary to activate autophagy.
    00:16:56 Whether or not time-restricted eating or 16:8 intermittent fasting reliably induces autophagy in any of our tissues.
    00:17:57 The important differences between prolonged fasting in humans and the rodent animal models used in studies.
    00:19:03 The 12-hour half-life of IGF-1 and whether or not that has any implications for the potential of autophagy in shorter duration fasts.
    00:20:12 The effects of long-term caloric restriction on markers of cellular autophagy in humans.
    00:21:32 The effect of an every-other-day eating pattern in rodents and how this pattern actually mimics the longevity producing effects of caloric restriction but with the advantage of stabilizing long-term at a more normal body weight. (Note: Dr. Kroemer is quick to point out that this type of intermittent fasting is more dramatic than it would be in humans because of differences in metabolism… the animals actually experience a 10% oscillation in body weight from this pattern!)
    00:24:35 The effect of exercise (especially endurance exercise) on autophagy in muscle tissue.
    00:25:08 The role of autophagy as a mediator of the anti-obesity and anti-diabetic effects of endurance exercise.
    00:26:58 The differences between macroautophagy, microautophagy, and chaperone-mediated autophagy.
    00:28:03 The difference between autophagy that is dictated by demand (nutrient stress) versus autophagy that occurs as the need arises to recycle damaged organelles.
    00:28:40 How damaged organelles change the composition of their surfaces in order to decorate them with signals for the stimulation of their engulfment by the autophagosome.
    00:29:07 The many, many names autophagy has when we are talking about it in the context of specific macromolecular structures and organelles (e.g. mitophagy for mitochondria, pexophagy for peroxisomes, reticulophagy for endoplasmic reticulum, ribophagy for ribosomes, and virophagy for viruses).
    00:29:35 How autophagy from nutrient deprivation still prefers to first recycle organelles that have been slightly marked… in other words, that are already aged or slightly damaged.
    00:31:15 How mitochondrial use ubiquitination, a process which occurs when these organelles begin to lose their membrane potential, in order to signal damage and to ensure preferential targeting by the autophagic machinery. ↓ mitochondrial transmembrane potential → ↑ ubiquitination → ↑ mitophagy
    00:32:42 The coordinated manner in which mitophagy and mitochondrial biogenesis act together in a closed feedback loop in order to preserve mitochondrial quality while preserving the total pool of functioning mitochondria.
    00:33:34 The changes that can occur in total mitochondrial pool as cells adapt to take on new metabolic profiles through a mitophagy-mediated process. This can occur as cells differentiate into new cell types that are specialized for glycolytic energy generation.
    00:35:13 The role autophagy plays in the prevention of neurodegenerative diseases caused by protein aggregates.
    00:37:18 How autosomal recessive mutations (where both parents must contribute a defective gene for PD to arise in the offspring) in a kinase protein called PINK1 disrupts its ability to recruit a protein called Parkin that mediates the targeting of mitochondria for mitophagy. ↓ PINK1’s kinase activity → ↓ parkin recruitment → ↓ mitophagy → ↑ accumulation of damaged mitochondria
    00:38:01 Mitochondrial membrane permeabilization as a death signal due to the release of dangerous proteins contained in the mitochondria.
    00:39:05 Dr. Valter Longo’s research demonstrating a cycle of prolonged fasting followed by a refeeding can recycle 28% of the white blood cells, and reduce the severity of an autoimmune disease (multiple sclerosis).
    00:39:52 The evolutionarily-conserved sickness response (food avoidance) as a way of beneficially altering immune responses through through altered metabolism and autophagy.
    00:41:02 The surprising increase in lethality that happens when mice are force fed (glucose in this case) while exhibiting sickness response from a bacterial challenge.
    00:42:27 The effects of an anti-malarial known as chloroquine which has some cytotoxic effects in cancer cells, but is actually (surprisingly) an inhibitor of autophagy.
    00:43:12 Studies of the lysosomal disrupter and anti-malarial chloroquine in combination with chemotherapy in the treatment of cancer.
    00:44:04 The differential roles autophagy plays in the progression of cancer in pre-malignant cells, when it is suppressed, versus in malignant cells, when it is sometimes used as an adaptation helpful to the survival of malignant cells experiencing environmental stress. ↓ tumor suppressor gene activity → ↓ autophagy → survival of pre-malignant cells → ↑ autophagy as a malignant adaptation
    00:44:49 How inhibition of autophagy by itself is sufficient to induce oncogenesis, particularly in leukemia.
    00:48:10 How cells undergoing autophagy can release ATP into the extracellular space where it can function as a signal that recruits and activates immune cells against tumor antigens through the activities of purinergic receptors. ↑ autophagy → ↑ extracellular ATP → activation of purinergic receptor-mediated immunosurveillance
    00:48:49 The importance of the triggering of this immunosurveilance system as part of the cell death associated with chemotherapy.
    00:50:27 The class of compounds known as “caloric restriction mimetics” that affect autophagy by perturbing various pathways in such a way as to reductions in cytosolic acetyl CoA and protein deacetylation in a manner similar to nutrient deprivation. Examples include: hydroxycitrate (inhibits ATP citrate lyase), spermidine (inhibits Ep300, a protein acetyltransferase), and resveratrol (activates deacetylases).
    00:55:27 How intestinal bacteria may produce as much as 1/3rd of the body’s spermidine and how this production rate can be manipulated by probiotic and dietary interventions.
    00:56:17 How the ability of caloric restriction mimetics (CRMs) to induce a type of autophagy that provokes immunosurveillance potentially offers an opportunity for synergy when used in combination with chemotherapeutic agents in the treatment of cancer.
    00:56:56 How the inhibition of autophagy in malignant cells or destruction of the extracellular ATP released by cells undergoing autophagy is able to abolish the favorable interaction between caloric restriction mimetic drugs and chemotherapy.
    00:58:02 The tendency for dietary consumption of caloric restriction mimetics, particularly hydroxy citrate, to induce autophagy and reduce weight gain in mice fed an obesogenic diet.
    00:59:17 Dr. Kroemer’s personal intermittent and prolonged fasting practices and his habit of consuming foods that may contain some natural quantities of caloric restriction mimicking compounds.
    01:01:40 The autophagy-enhancing effect of coffee (with and without caffeine).

  • Hi Dr Patrick

    I was wondering what you think of the ‘Snake Diet’ which includes an intermittent fasting lifestyle. Is it safe to drink water with these ingredients while fasting? Will true autophagy occur? The creator of the diet says you lose too many electrolytes while fasting for longer periods like 48,72, or more hours. He says you need to replace lost salts and potassium while fasting or you will feel shaky.

    ‘SNAKE JUICE’ Water RECIPE

    Per 2 Liter H20:
    (Evian bottled water recommended because of PH)

    *drink less than 2L per day of the bottled water mixture*

    Potassium Chloride Powder = 2 tsp
    (4700 mg) -(No Salt brand or Windsor salt free)
    Himalayan Pink Salt = 1 tsp
    (2,000 mg/L)
    Organic lemon Juice 8 Tbs per day
    Organic apple cider vinegar 4 Tbs per day

  • I just found out… That at Norwegian nursing homes. They measure vitamin D blood levels and adjusts diets and supplements to keep it always above 50 ng/ml. I am actually impressed…. Well done socialist medical system in Norway.

  • Top 10, or even 5 here Rhonda, this was an exceptional interview! There is beauty in science, you know how to waltz with intellects and match them step for step. There were so many “connect the dots” moments for me in this one, I’m sharing it far and wide, and coming back for the encore. Bravo, and many thanks to Guido for coming on, he clearly appreciated your considerate, intelligent interview style. So grateful for your work, thank you.

  • Dear Doc, you did perfectly support my opinion/comment in your Sweden video. My feeling is that the cross-immune ones’ percentage makes the big difference, as most of us are quite adapted to fight conventional cold-CoVs. As to the vaccine topic, thanks for your “renormalizing” statement!

  • According to the official statistics, South Africa has turned into one of the greatest epicenters of Covid-19 in the world. Since the beginning of April to the 12th July, the cumulative number of infections in South Africa has doubled about every 14 days. On 12 July 2020, 264,184 cumulative cases have been recorded, slightly more than double the 131,800 on 28 June, 14 days before. South Africa was firmly on track to record half a million cumulative infections by 25 July. Community spread appeared unstoppable. At that rate of increase, 1 million would have been infected by 8 August, 2 million by 22 August, 4 million by 5 September, 8 million by 19 September, 16 million by 3 October and some 32 million by 17 October 2020. That would represent 53% of the population of over 59 million people. The daily number of new infections should then have dropped off steeply. On that trend, over the first two weeks of October, between one and two million new infections were likely to occur daily.

    However, on 13 July, the number of new cases dropped significantly by about 1,440, or about 11%. The day before, the 12 July 2020, sales of alcoholic beverages were prohibited in South Africa, creating a false impression that the ban was the cause of the drop in numbers. However, this is false, because the normal lag period between the introduction of a new, effective measure and its effect was completely absent, clearly identifying it as fake. This trend of a reduction of new cases continued daily and appeared to become progressively stronger. The result was that, today, 21 August, the official cumulative number of cases in South Africa stands at 599,940, instead of about 2.48 million, had the ‘trend’ of doubling every 13 or 14 days continued. There is no rational reason for a ban on liquor sales to cause such a sudden, steep drop in new cases, hence the conclusion is that, over the three-and-a-half months before 12 July, the numbers have been manipulated up, as were the numbers on recoveries. Death numbers, on the other hand, were manipulated down:  https://www.businesslive.co.za/bd/national/2020-07-29-excess-deaths-soar-to-more-than-four-times-official-covid-19-toll-mrc-data-shows/.

    The question is, why have the number of cases been manipulated up?

    Early this year, South Africa applied for an IMF loan of US$4.3 billion at a very low interest rate. On 27 July, the IMF publicly announced that the loan was granted https://www.imf.org/en/News/Articles/2020/07/27/pr20271-south-africa-imf-executive-board-approves-us-billion-emergency-support-covid-19-pandemic. Most likely, South Africa was informed of the grant earlier than the public announcement, perhaps around 12 July? Clearly, the numbers in South Africa have been manipulated up to impress on the IMF an urgent need for funds to fight the epidemic in the country. Most of the funds are likely to land in the pockets of corrupt people in positions of power and their family.

    A further question is, what is the real motive for the ban on liquor sales?

    The answer is that the ban on liquor sales will most likely drive many liquor stores out of business. The liquor trade is seen as lucrative, easy business. White owners of such businesses are exempt on a racial basis of financial assistance to weather the covid storm, including the IMF funds. Many of these businesses are likely to be bought up at bargain prices by black politicians, their family members  https://www.dailymaverick.co.za/article/2020-07-31-ace-magashules-sons-each-bag-a-free-state-covid-19-contract/amp/?_twitter_impression=true, and other black business people, perhaps using some of the IMF funds paid for other contracts where contract prices have been loaded https://www.news24.com/news24/southafrica/news/covid-19-sahrc-set-to-probe-gauteng-health-spending-amid-corruption-claims-20200730

    And  https://www.dailymaverick.co.za/article/2020-07-30-province-to-disclose-ppe-procurement-details-to-avoid-corruption/

    And  https://mg.co.za/coronavirus-essentials/2020-08-06-the-ppe-scandal-that-the-treasury-hasnt-touched/

    Fraud and corruption assume many a guise. The South African government is rotten through from top to bottom and doing the population a grave disservice by spreading false information to serve the aims of people in power to enrich themselves. Never miss the opportunities a good crisis offers, hey?

  • Its very difficult for me to cognitively induce or restrict mitosis on trillions of my cells. How they heck am I to now induce all the different types of autophagy? I won’t have time to eat anything, now or later. By the time I get this figured out, the next phase of published research will contradict all this.
    Call me when they make a pill

  • Nicely done, even though most has gone over my uneducated head love how you add illustration and definitions et al.Having to educate myself having been recently diagnosed with cll and given NO advice on exercise, diet,just wait and see is the standard. Keep up your good work.Thanx

  • When viruses replicate, have scientists kept track of a total ELEMENT-BALANCE:
    carbon atoms, nitrogen atoms etc? This is something I should force MYSELF to do.
    Where do all these C, N, O, H atoms come from to form new virions?

  • Our immune systems are pump primed by viruses and bacteria every idiot knows that, what is all this rubbish, please use less emotive language! Given the current climate politically speaking, i would have thought you would appreciate this, maybe during the 2nd world war, you would have been a valuable asset to…?

    Otherwise, some interesting stuff but the study of viruses is in its infancy still and it is multi factoral on all sorts of levels.

  • Excellent information! I would like to point out that the Resveratrol is found in �� grapeskins, which is why it shows up in red, not white, wine ��, thus, the risks of alcohol may be avoided. Carry on! ��

  • All good Dr Syed over the last few months the papers have been coming in thick and fast showing antibodies ARE NOT the be all and end all The Dark Matter is coming to light!! from June 4th https://www.youtube.com/watch?v=dUOFeVIrOPg

  • Rhonda, I haven’t heard you speak yet about the carnivore diet. I am doing carnivore plus warrior. I call it wolverine diet. What is your take on it?

  • Wow, that’s so interesting and refreshing to have a smart person explain all this.
    (Unlike the current flood of &*#% that we get from the network TV channels.)

  • Dear Mrs. Glaunsinger, back then Robert Koch articulated some rules for reseach in the field of virology. One rule was that each new isolated virus has to be verified in experiments in order to show if it is capable of killing living organisms by infection! To my best knowledge this was never done even once till today! I remember well what the molecular biologist Dr. Peter Duesberg had published about the lies of the HIV-Virus and what the biochemist Dr. Kary Mullis (nobel laureate of 1993 for chemistry) had published about the missuse of his PCR-method (“Polymerase-Chain-Reaction”), which he had developed.
    Look at the death rates world wide! E.g. 20.000 deaths EACH DAY just for China (!)… or more than 7400 deaths EACH DAY in the USA alone (close to 1% of population per year). So people are not dying because of a “virus” (which in reality are just DNS/RNA-fragments) but on AGE, on UNHEALTHY FOOD and of the lack of daily movements causing overweight, which as a consequence weakens their immune system significantly! Dying of a cold is just proofing that their immune system was already damaged drastically… for many reasons… e.g. the consume of their daily amounts of medicines… many call all this… LIFE!
    If a pandemic would be real, you could ask the undertakers if their numbers of weekly funerals are increasing significantly… but that is NOT the case!… so why always all these panicing academics?… singing the accepted orthodoxy of science (Thomas S. Kuhn)…
    Or does the pharmaceutical industry have wet dreams?… hoping to sell expensive vaccines world wide?… even worse… hoping that their marketing department called WHO and governments around the globe are forcing their citizens by law to get these expensive vaccines?… and let them pay of course… leting them die on drugs like it happend back in 1918/1919 for treatments of the so called “spanish flu”.
    Remember (!) the numbers of dying AIDS-patients did not raise significantly before and until they got their AZT treatment end of 1987… AZT is also used in rats-poison (!)… SO… UNTIL any virologist on the globe is able to execute the experiments in the laboratory which proof that a “virus” is capable of killing living organism by INFECTION (!)… I am convinced that “virology” is nothing but pseudo-science!

  • IT is funny to me when yu were interviewing dr. Longo who actually could answer your questions on when autophagy began, you did not listen to him and now you are asking a man who has not done that perticular research. You also ask him if he knew what stimulated the onset of autphagy. Dr. Longo answered those quetions. You might want t watch his videos when reviewed by people who let him talk more. HE said that in order for the autophagy to begin first the liver must mark the cells to be eaten which occurs after all glucose has been depleted. Once all glucose is removed which typically occurs after day 2 then on day 3 the liver marks the cells as keepers or eaters… then when all of this is marked cells is completed the body begins to eat both fat and the marked cells.

  • This Dr. Syed helps restore my confidence in the medical community. He makes sense. I will say, however, that he tends toward scientist-ism: that is to say, he will happily pick nits from obscure data for days on end, giving unfortunately short shrift to important bigger issues. What about, for instance, the negative effect of keeping recovereds out of society rather than returning them so that their personal immunity can support overall herd immunity? Another critical issue would be whether or not many more lives could have been saved if we had more quickly focused on care/recovery versus containment/avoidance. Also, why didn’t we have accurate, cheap, simple tests much sooner? Should we expect quicker tests in the future? Another pandemic is on the way. How should we prepare for it? What should be our plan for that eventuality? Why didn’t we look at the very clear characteristics of this virus super contagious, quite survivable with actually not much care (bedrest/nutrition primarily) and reason that the best response would be care/recovery vs containment/avoidance? This is all off-the-top scattershot, but there are important big issues to discuss. And I’d like to know why was Sweden so smart, and the rest of us so dumb?

  • How intelligent is this guy! Wow, a knockout interview. Also, I can tell you took the time to edit the closed captioning, which isn’t easy or quick. Wanted to express my appreciation for that, because having captions on helps me concentrate and retain information. Thank you for producing all these high quality, informative videos.

  • My thinking is that Dr. Patrick is pretty humble.
    I feel fortunate every time I watch one of her videos
    on whatever subject I have ‘searched out.’
    She’s like a modern-day Leonardo DV that we
    get to watch on you.tube����

  • If the R number was kept below 1.0 by NPIs would the result not be the same? How would we distinguish this from “herd immunity”? With an R number below 1.0 the virus would find fewer and fewer hosts over time, which would produce the same geometric decline in cases and deaths seen in Sweden and elsewhere in Europe. I am not familiar with the time line of the epidemic in Sweden, but this “herd immunity” idea has been put forward for London, where I live, as our cases have declined and stayed low so far. However this ignores the fact that London had an effective 3 week lockdown, less effective after that, and almost complete shutdown of the public transport system. In London the lockdown bought the cases down and since then the NPIs have kept the R number below 1.0. We cannot tell what would happen if we had the buses, trains and tube running again at full capacity AND then 1000s of infected people arriving in London from Europe like we had in early March. If we look at other places where the virus has been left to run its course like Iran, Brazil, or Peru we do not see the geometric decline in cases shown in Sweden and the rest of Europe. There is no sign that without intervention the virus meets a fire break of pre-existing immunity. Seroprevalence is over 60% in parts of Peru.

  • Very positive…. happy ending
    We are naturally armed against COVID-19
    NK Arm…. Killers… Marines
    CD4+ Arm…. Helpers…. Gunships
    CD8+ Arm… Cytotoxic.. Tanks
    B Cell Arm… Memory…. Carpet Bombers
    luv it

  • Fantastic interview, even more remarkable when you think that English is the second language from Dr Kroemer! He speaks better English than most of us native speakers.
    I find that the people with the most knowledge and intelligence are very calm and don’t let their emotions get involved with their answers.
    I didn’t understand everything he was talking about but bit by bit, I am getting very interested in fasting and autophagy. When a man like Dr.Kroemer is on OMAD plus prolonged fasting, not to mention wine and cheese! That is good enough for me
    Thanks and keep them coming!

  • Thank you for such an insightful interview and information!
    Durian was mentioned. Just curious how this “king of fruit” can influence our health. I know it’s very complex and rich food but that agent producing strong smell as I’ve heard in this interview could have some benefits (or not). I’m sorry that I didn’t get it clear from this video.

  • I wish polyamines such as putrescine, spermine and spermidine were available as nutritional supplements. It’s odd that they’re not. I’ve seen spermine advertised on Amazon, but it’s as a laboratory product, not a product intended for human consumption.

  • This is why I don’t trust the scientists who ignore the theoretical and mathematical foundations of science like entropy. Viruses do not evolve. If they tried to evolve in human conception, they ended up the end of their dependent life or of their functions due to the mathematical principles of science which were originally designed and controlled by God. In the same way, it is proven that in bacteria every mutation failing from the designed genome is leading to dysfunction or death in the worst case. Likewise like cancer in the human body all mutations are led to diseases, not evolution nor any improvement but devolution or dysfunction or death. Mathematics and theoretical science are not limited to Physics or to Chemistry but also to Biology. Surprisingly, many biologists are not well equipped with such Theoretical Mathematics and ended up producing many errors. The funniest things are that many molecular biologists have stolen a tiny piece out of the knowledge of the life designed by God and then they soon disregarded the creator, and claims that the technology without knowledge supports the theory of evolution erroneously. How stupid the world is.

  • Rare to find a raw, unfiltered podcast that focuses on the science, without dumbing it down to pander to the audience. I didn’t understand a lot of the cellular mechanisms entirely, but the numerous papers being cited, motivate me enough to find out. Dr Guido seems like on of the most knowledgeable persons I’ve seen on your podcast, its impressive to hear the breadth of his knowledge.

    P.S Spermidine in cheese in synergy with resveratrol in wine, would be interesting to see if this is a reason behind the French longevity paradox.

  • What about practising both intermittent fasting and caloric restriction? E.g., consuming under two thousand calories in a four hour window? Would there be multiplicative benefit or am I wasting my time?

  • Yes, protein depletion has been tested on humans and protein deprivation has been practising for many years, but for the past 25 years in very large numbers at the sanatoriums of Dr Emilova in Bulgaria. Hundreds of thousands of people have been there fasting under doctors supervision and the data shows improving the health of all of them. You say here, we don’t know. Yes, we do know. Its documented. And fasting could be done not only for more than 24 hours, but as long as 30 days eating fruits only. My own experience from it is also amazing. Of course fasting should always be done under doctors supervision as some conditions could get worse.

  • It’s fantastic and I couldn’t be more thankful that you,special person, share with the whole community such infinitetly valuable informations. It’s remarcable that you share whole interviews full of awesome infos,my deepest regards for all your work and for sharing it with us. I wish you all the best!

  • 52:43 so if I’ve got this right… If I stop eating for 2 weeks, run a marathon & then neck a celebratory bottle of red at the finish line then my autophagy levels will reach heights never before seen & I’ll live forever?

  • so i guess when i comes to introduce autophagy as fast as possible it is perfect to be on a ketogenic diet, where the glyogen fuel is already cut off. so i guess it is just down to the aminoacid pool to get empty so that the autophagy starts.
    in january i did one meal a day on keto (being on keto for a year) and i lost 1kg of weight per week without being hungry and i think a also got a little bit younger. but in february i boosted it by sometimes eating every other day or even every third day and sometimes also doing a dry fast for two or three days. i don’t do much exercise but my running performance significantly improved in that month (without doing much exercise in between!)
    i do not plan to eat more then one meal a day for the next half year. and i hope i can do more three day (dry) fasts. the outcome is fantastic. my skin gets much better and my energy level also gets better.
    well i have to do that anyway because i lost 25kg of weight in the last year, completely reversed my diabetes typ 2 and i still need to again lose 25kg to get to my ideal goal weight and have nice 6-pack abs.
    and i guess the autophagy is a good way of tightening my skin. i think i am on the right track here, because i would just do carbohydrate calorie restriction with three meals a day i would be hungry and therefor angry all day and at the end i would look like an empty old bag instead of a fresh tight young boy:-)

  • Many thanks, Prof. Deshaies, for the video. As a synthetic/medicinal chemist and pharmacist, I would like to work in development of PROTAC molecules, for cancer and neurodegenerative diseases. I have been reading a lot about… Many thanks for sharing your knowledge.

  • Hi, thank you for speaking up about this protein related to Angelman Syndrome. This is a debilitating but curable disease that affects children. So vital to support research to eliminate it!

  • Great video! Just one remark… On min. 11:13 concerning the human diseases, don’t you mean Angelman syndrome (instead if Angleman) and isn’t it a neurodevelopmental disorder (and not neurodegenerative)?!

  • This is a really great presentation and very helpful, thank you. The point about certain proteins needing to be unstable to enable rapid changes of steady state in certain areas of cell biology to be possible, is very interesting.

  • I’m literally over the moon to find this 2nd lecture from Dr. Glaunsinger. I was amazed to view her lecture on SARS-CoV-2, coronavirus as I prepared for one assignment in my MS in Organizational Leadership Course titled “Understanding Data”. I’m researching the CDC & for the entire eight weeks of the course, I am asked to solve one or some of that agency’s problems. These lectures have given me a huge advantage to making a substantial contribution; therefore, I am gratefully indebted to Dr. Glaunsinger for her expertise & phenomenal lectures. Many, many, many thanks!!! Can’t wait to see her leading one of our federal agencies. Keep up the awesome work!

  • A perfectly brought presentation (an example to a lot of scientist) that actually brings one truth extra: never underestimate the enemy, instead…respect him…

  • Perhaps naturally weaken viruses have always been the key to herd immunity. More percentage pf the population are exposed, creating immunity, and because the virus is weakened, less mortality and less morbidity. Sounds like great news, and reason to be cautiously optimistic!

  • She knows a lot about the virus hoping she could make a solution to stop this…
    A vaccine —that can help all of us ———more power to you frof.

  • I don’t get how everyone’s talking about caloric restriction and fasting, but never goes into how some of us should SURVIVE a lifestyle like that. If I restrict my caloric intake by even 25%, I’m gonna lose weight and eventually… well, die?!

  • Olá familia da ibiology, estarei compartilhando o canal de vocês, não entendo sua linguá mais gosto da informação, wagner Conselheiro local de Saúde de Barueri SP Brazil

  • Thank you, I learned a lot. Unfortunately, my high school level molecular biology classes are insufficient to understand all of it (I am an aeronautical engineer).

  • Brilliant news Dr Been! I guess despite Sweden’s controversial, socially relaxed, viral outbreak mitigation strategy, like you say, it has become a lab rat or guinea pig for the rest of the world to observe and analyse data about the natural behaviour and public health implications of SARS-CoV-2 virus. It seems very much a “hit and run” or “crash and burn” type of virus, unlike HIV for example which kills slowly and has been ongoing for decades due to it’s deadly characteristic of laying dormant in human cells and never being properly dealt with or eradicated by our natural immune systems. SARS-CoV-2 on the other hand, caused a lightning fast spreading, hard-hitting, high-impact, pandemic situation but seems to already be in retreat as worldwide fatality rate is certainly in decline compared to the first initial phase of the pandemic and the virus itself appears to be burning out as our immune systems adapt and the virus, effectively, has less places to go. Maybe we are finally starting to get it into a corner and the vaccine will be the final bullet in what is already a pathogen in retreat. I really do hope so. Keep up the good work Dr and thank you for all the information and data you present to us. Stay healthy and stay safe.

  • Sunetra Gupta was right months ago. Many others too. The peak in Europe was before lockdown and most of us have been exposed to and fought off the virus with mild or asymptomatic infection. Muchael Levitt has crunched the numbers too. 500-600 deaths per million or roughly one month’s worth of excess deaths. Neil Ferguson got it completely wrong; as he has so many times before. Unfortunately too many policy-makers believed him and the media have played an awful game of fear-mongering.

  • I honestly TOTALLY forgot about CIRCULAR DNA inside a virus or bacterium from my biotechnology courses. I got an excellent education. But it’s hard to remember this stuff (after 10 years) when you don’t use it, when you don’t have a job that uses it.

  • Enzymes DO NOT CHEW ANYTHING where do you get all this corny stuff from you to have a phd, apologies again, I haven’t been in a lab for many years but it appears there are many interpretations, viruses can they really be studied properly or in-depth ex-vivo or outside the host?

  • Dr. Britt, you are wonderful. Great corona virus lecture too. I see the department is plant and microbial….I’d love to hear you discuss the Sunn-hemp mosaic virus sometime.

  • I have had the biology,chemistry, physic, higher mathematics and even basic quantum theory, but never have I felt so indebted and appreciative of Phd professors and lab directors who take time to teach us on youtube. Thank you so much for this video series.

  • Since a virus cannot decide to do anything that begs the question…is it natural selection or a designer that got the virus going in the first place.

  • Apologies for being personal but you are running through extremely complex cell biology at a huge rate of knots, might do to slow down a bit t for those of us without a phd.

    You have made some lovely points but one cannot get around the fact that you still seem unable to stop using terms such invade, “steal them from the host”.

    How do you know hosts do not allow a degree of so-called invasion, as they are proto life forms billions of years in evolutionary tandem with eukaryotes.

    Yes they can produce what from a human perspective disease, ie potato blight and so forth, but even this was a lot to do with the way we tried to cultivate them, viruses are viruses so-called neither good or bad, but yes fascinating.

  • The disease only wants it’s pound of flesh, then it will pack it’s bags and leave satisfied.[not going to be greedy] You just have to pay the piper then he leaves.

  • I want to help. Do you think we could build a system of minions where those like you, Britt, can relay the very next step in your research to fans who may not know much but want to learn and participate? Maybe some analog to sports fans. I can’t perform like the pros, but I can watch, appreciate the moves, and help predict what could happen next. Any thoughts? How can we spread the load of improving human progress in this field? Thanks for what you are doing.

  • One way of interpreting viral inclusions in our genome is that they started from the genome and are exported by an as of yet unknown mechanism. What kind of experiment could refute or confirm such an idea?

  • I’ve recently stumbled upon this channel and let me say that both of the videos I’ve seen so far are great. Who ever writes their script needs a raise.

  • How easy is it to track the origin of a virus? Covid is from China and that is not the first time but, There are other countrys with simular density but why is so few virus from these places? Does geography or culture increase creation of virus?

  • Maybe their programming comes from the outside of them, competing teams of entities, kind of a very large spirit-level video game outside of our physical lives. The long-term effect over eons is to make our physical form more resilient, could be useful if we go all Star Trek on the universe eventually

  • Thank you very much on your expertise and explanation about viruses. This is extremely helpful.

    Viruses actually start out as part of DNA protein in living cells of living organisms. So they do not begin as viruses. As DNA sheds excess and waste DNA and RNA these split, each dividing into a single particle of protein, while still harboring the force of life. It is this force that gives it animation, mobility, within organisms. These usually move harmlessly through he parent organism, through body fluids such as blood, mucus, saliva, intestine secretions, etc. It may be that the parent organism has natural biological mechanisms that keep the waste protein from replicating as it naturally does when it is part of DNA or may it prevents it from accessing cell receptors in the first place. These proteins are often expelled from the body through spitting, coughing, sneezing and through the bowels. These active proteins with either DNA or RNA strands usually end up inert and harmlessly on the ground. They will remain viable yet inert for a relatively short time until they become completely inactive. These proteins are called viruses when they become radical and infect a parent host, which rarely happens. Most often they become viral when they become reintroduced to a foreign biological host organism and infects it. Some hosts may be able to easily quench the virus depending on its natural immune response. But other organisms will not be able to eliminate the virus. When a virus gravitates to cells that have compatible receptors they latch on to them and enter he cell, make contact with the DNA of the cell and naturally replicates itself over and over again until it overwhelms the cell and the cell bursts or dies otherwise. This is what triggers a stronger immune response and the infection is a symptom of the disease caused.

    I hope this may add to the clarity on the subject.

  • Damn… when I watch such topics I always realise how little I know., yet each time learn a little bit of something new. Hard to grasp when lacking In fundamentals, nontheless an excidingly amazing lecture told by a beautiful and very charismatic woman:)

  • Wow, viruses are such intelligent creature, how sophisticated it manipulates and hacks cellular machinery.. how can such simple and compact RNA/DNA snippets could do such things.. ����

  • Madam. Where did you get this large knowledge about ubseen small virus. If virus using our cells to use for replication why our cell smoothly allow that? After destroying our cells what happens to our cells? Do you have any microscopic images of cells that destroyed by viruses.

  • Legendary as always, keep up the awesome work Rhonda! Really appreciate your non biased, scientific approach to the information you share. You seem to have constant access to the latest scientific evidence. An idea I randomly just had was to have a “literature review webpage” of sorts, whereby you post 100 words or less (for example) on the strongest scientific evidence for various topics such as autophagy, fasting, caloric intake, CRM’s, etc with a focus on what the current optimal approach looks like based on the latest evidence. It would be amazing to have a constantly updated reference guide (maybe every 3-6 months an update) where people can go to see an unbiased literature review essentially. But a lot shorter than a typical review. Hope this is an interesting concept for you. Cheers from NZ! Rock on:)

  • Excellent introductory video on viruses. Interesting and informative, and a must see video for everyone with even a passing interest in viruses.

  • Grrrrr…the emergent properties of viruses are truly incredible, but, that their economic information allows them to be so symbiotically adroit, is so annoying. Yet, I’m sure they are the pre-missing link to the step which explains the abiogenic origin of life, which is why they are here today. I hope to live long enough that science finds this step out and finds a naturalistic explanation for the conditions that allowed it to happen, If not, it would be great to be rid of the herpes zoster in my cells or cure type I diabetes which I’m sure has a viral insult vector.
    Great and Very Important Work Dr. Glaunsinger!!! Overwhelming thanks to the teams who make viewing this possible to the world!!!!!

  • DrBeen, this is very interesting! The additive impact of your 4-5 various contributors towards HI (herd immunity) might also help to explain the two cruise ship outbreaks early on in this pandemic that became a real conundrum as to why more people didn’t test positive, get very sick or die, correct?

  • great work, but you lost me on logic at 8 minutes in, little tip, zoom in to 1 virus group as example like the hot topic one corona or influenza.

  • 26:20. Interesting you ask about the Exercise while Fasting. I have been doing 16 hour fasting and find it great for energy (Mental) and weight loss (Fat). Personally I find it really efficient to exercise at the 14th hour for about 30-45 minute run and then eat around the 15-16 hr to break the fast. I no longer have a 3pm low energy and have been loosing weight this way.:)

  • Nice lecture, but scientists shouldn’t talk in a way as if micro organisms or viruses act intentionally. Like “How does the virus figure out something”. That’s what feeds the doubt that these things can even happen. Because they don’t. No virus figures out anything. Things happen when things happen. Yet, many scientists speak in that wrong way around fashion.
    “Evolution has found a way.” No it hasn’t. Stuff just happened to work out.

  • 1:50
    “8% of our genome is from viruses.”
    No. That isn’t true. She is referring to ERVs.
    ERVs are not from viruses. Humans and chimps were created separately. There are many ERVs that are in the same corresponding location in the genomes of both humans and chimps. If ERVs are from viruses then the probability of this occurring is 0. Therefore, ERVs are not from viruses.

  • Herd Immunity is a lie. Covid-19 is a constantly mutating bioweapon. After recovery it leaves behind impulse symptoms that turn into cancer and/or organ failure or multiple organ failure.

  • I’m no expert on this but I think it’s probably difficult to draw conclusions by just looking at the statistics without understanding what is actually going on in Sweden. The truth is that a lot of things have changed. Maybe we’re close to herd immunity in the capital area, personally I don’t think we’re there yet, but in the rest of the country I can’t see how we could be anywhere close.

  • There is a world of difference between career political epidemiologists like Dr. Fauci setting world policies, desperately trying to remain relevant and in power and the actual honest non-politicized scientists in the world. listen to what the leading microbiologist’s that make the vaccines are actually saying about a vaccines availability likelihood and effectiveness, How weak the viruses virulence actually is from what is now known from the data and who is at risk and who should be taking precautions, while the rest of the population allows the infection to run its coarse to acquire natural antibody T-Cell immunity to snuff the virus. globalnews.ca/news/7085775/coronavirus-vaccine-false-hope/ https://www.youtube.com/watch?v=l1FFKT_VZ5c

  • One thing that would be true by now would be the reinfection cases. This far there has been 0 cases of reinfection in Sweden and around the world we should have heard of thousands of reinfection cases by now if antibodies are our only protection (15-20%?). That meens 80% are without protection and no way that they are soo lucky or good at protecting themself there should be alot of cases where reinfection should have occurred. We all know how eager media is about reporting bad news but nothing about it must meen tthat there arent much cases to report. Immunity must be the reason. Immunity and social distancing should meen that you dont have to have herd immunity levels to slow down the spread. Maybee 40-50% immunity is enough combined with other mesures. By the way no masks or very little of them in Sweden. Tegnell is saying why use masks now when numbers are low. If they change then he will reconsider. There are more stuidies about immunity that confirms what you are saying. https://www.youtube.com/watch?v=D5Z6wdu1eI0&t=1s

  • it is unfair that gavin newsom keep his wineries open and enjoy millions of stimulus but he forced self employed businesses to be closed down just because they are non-essential
    , also 2008 was rigged to destroy libya
    https://www.youtube.com/watch?v=PJkK_gTOMGQ
    https://www.youtube.com/watch?v=_mrJRHwbVG8

  • For Sweden, what is needed are the covid-19 cases age cohorts over time, to see if any correlations with past and present death rates.

    The following journal paper analyses how a country’s population age demographics, and the covid-19 deaths with each age cohort, impacts on the observed covid-19 Case Fatality Rate (CFR). They conclude that age cohorts explain 66% of the variation of CFR between countries.

    https://www.acpjournals.org/doi/10.7326/m20-2973

  • 1 The Swedish belated physical distancing measures (& PPE), plus covid-19 testing of healthcare staff in aged care facilities should have eventually reduced covid-19 infections and deaths in these facilities (lockdowns in facilities introduced late).

    2. Don’t forget the significant increase in testing and self isolating of positive cases will have an impact on community transmissions rates.
    This was a major factor with New York State too, eg Sean Penn campaign, donated money for testing, contact tracing, so positives could self isolate and stop community transmissions.

    Note, Sweden has dropped the number of covid-19 testing in the past month.

  • This was an amazing presentation!! It really helped connect the dots on how these mechanisms can dictate the outcomes in health and disease. I would certainly be interested in your thoughts on his personal regimen of prolonged fasting, exercise and diet. You are doing a great service to all of us.

  • Please see Swedish system of Covid control people of age Refused Oxygen (Murder) by Government Decree Ref Dr Jon Tallinger Whistleblower. They not care for their own elderly.

  • Pakistan stopped lockdown (announces that lockdowns are bad) at 9 July, then got the fast epidemic rise followed by the fast fall down. Proofs population immunity too.
    South Africa, proofs it too. Many countries follow now by showing it by their stats too.
    MANY WEST EUROPE COUNTRIES HAVE A HIGH LEVEL OF POPULATION IMMUNITY BUT DON’T KNOW IT YET!!!

  • Wonderful. Thanks for taking the time out from your research to develop and script this presentation. Thanks to the people that helped you and to NSF and NIH for sponsoring.

  • I am thinking the virus might not be easily transmitted outside specific circumstances and people that act in a dangerous manner are a minority. This could explain some of the graph. What I try to say that some groups have R0 of much above the average, making initial R0 much higher than it would be for “average” person.

  • If you examine the data from the Diamond Princess cruise ship, that has been available since February when I first analysed it, you will see that in a population older on average by most countries at 65 years herd immunity was achieved under the most ideal conditions for the Cov-2 virus at 20% of the population, of whom 46% were asymptomatic giving you your 11%. It was obvious then and being confirmed now that most of the population has innate immunity to this virus probably due to previous exposure to one of the common corona rhinoviruses that attack the respiratory system. The experts have shut down the global economy through incompetence and the politicians through fear of taking the correct decisions.

  • Another GREAT video, thank you! Could you please keep us up to date on your research on probiotics and Spermidine? https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023652

  • Excellent presentation. In the UK we failed our vulnerable people in care homes, but then turned our back on Sweden leaving them looking like an outlier. Maybe in our more densely populated country it wouldn’t have worked as effectively, but if Sweden end up looking like their approach was a sensible strategy, we could probably learn a lot in tackling future virus pandemics.

  • People from 1 to 30 years of age in Missisippi are the largest group of those infected. Why? Their behavior is condusive to infection. Those above 60 have a high death rate, but they APPEAR to have much less infection. But that is an illusion. The are afraid to go get tested and so they are tested less. They are afraid to go to the doctor for fear of catching something at the doctor’s office. These 60+ year olds die more because they WAIT until the cytokine storm hits them. They go get tested only once they get really sick and panic. It is complicated.

  • There is a type of natto that tastes perfectly fine, even good; it is black soybean natto. I don’t know whether it is nutritionally different from regular natto; I’d be curious to know. It is the same mould that makes it, so probably it has nattokinase like normal natto.

  • Study about garlic essential oil inhibiting SarsCov2 and it’s protease and binding to AcE2 receptor
    https://pubs.acs.org/doi/10.1021/acsomega.0c00772
    We need a study to see it this helps in the Math + protocol adding 2mg essential oil caps. It may even help the coagulation as garlic is anticoagulant to some extent.

  • Prevention is the answer. e.g, take zinc with green tea, 10g vit C (2g x5 times), selenium, vit K2, quercetin, NAC, antivirals etc, & maintain blood level of vit D above 150nmol/l.

  • We need to see sales records of vitamin d in different countries.
    Vitamin d sales must have increased the question is by how much.
    Amazon would have some of that data at their fingertips.
    Percent increase of their sales over the past 8 months.

  • You notice that NY’s peak is two months ago and now they are in stage 4 reopening and NO OBSERVABLE RESURGENCE. So while they relaxed restrictions there was no resurgence. The empirical “new daily cases” data PLUS knowledge of mitigation efforts is sufficient to suggest that herd immunity is building in Sweden and NY. Your scientific papers simply provide a MECHANISM. I pity places like HI that had strict lockdowns and quarantines they’re going to have a resurgence and we’re seeing it in many regions. I am inclined to agree with your hypothesis and time will (hopefully) add to our confidence in it!

  • The New York Times reported which NYC neighborhoods have the highest rates of COVID antibodies.
    Where I live, East Elmhurst NY, the rate is 45.7 %. Full report is here:
    https://www.6sqft.com/nyc-covid-antibodies-by-zip-code/

  • The treatment of animals in experiments is just so wrong, thankfully we have organisations like Animal Free Research UK changing things. Mice eating each other because they are so hungry will be a thing of the past soon, and every cage will be empty.

  • Japanese scientiste Yoshinori Ohsumi has descovered the autophagy/self-eating or destruction, and he has obtained Nobel prize for that descovery which consist on how cells recycle their content.

  • So much new findings, developments and technical improvements plus information sharing, hope we can resolve the ultimate mysteries on viral/bacterial biology and bring those infections under control soon. The world has suffered so much for so long in human history.

  • The Swedes DO NOT wear masks. Their health authorities advice against it and if you wear of masks people will laugh of you and ridicule you.

  • Hi Drbeen,

    Interesting as always. Things you missed

    Sweden removed politics from the debate by putting the epidemiologists in charge of the response.
    50% of Swedes live alone.
    Large gatherings are restricted.
    Swedes have restricted their travel and have circa 70% less social interactions than pre-pandemic..

    Around 80% or more Swedes adhere to social distancing.

    The economy fell by 8.6%,
    Swedes have not gone out, ‘and are out and about’, young people continue to go out and spend. Older people restrict their interactions. Hence the economic falls and reduced footfall..

    I suggest that most people in Sweden who are out and about have contracted COVID, hence the falling rates. I propose that herd immunity is being achieved amongst a limited subset of the population, while others hide. Not (unfortunately) some miraculous immunity to a disease not yet met. Thus Sweden may still have a long way to go, especially if those hiding venture out.

    I do hope I am wrong Drbeen and you are right!

  • Good presentation, I dont think that emunity is at 11%, its far higher. Good hygien and social distancing make it hard for the virus to spreed. But it will increase again if we let our guard down. Today Sweden has less average daily dead than a covid free year. The General health of people, the age and amount of virus exposure looks importent for the deadlines of this virus. Mabey with all this global information about the virus we can make much better computer simulation in the future =)

  • Have they achieved herd immunity? Is there any data? May be there are less sero positive people and more people with activated T-cells

  • A virus that is weakening sufficiently would cause people to become more comfortable with the virus and thus they would interact with more people and infect more people, but because it is a sufficiently weaker virus, people would not feel sick enough to prompt them to go get tested, thus causing the detection to become less and creating the illusion that there is less infection when there is actually more, albeit less sickness-causing.

  • 18:38 The 27,000 is only for Stockholm elderly care homes so you need to scale that up by 10 because population of Stochlkholm is about 970,000 out of the 10m in Sweden. That’s going to give you about 280,000 in care homes if it’s similar across Sweden.

  • 2:30 THANK you for FINALLY giving me a NUMBER about the KINETICS of viruses.
    Seriously: I find EXTREMELY little DATA online (and thanks to quarantining I cannot access libraries) about the KINETICS of large biomolecules (large by comparison to simple compounds, like CO2). I am sure such data is EXTREMELY hard to tweeze from experiments.

  • So….we now know…that beyond the Lysosome…that we’ve known about for 30 years…that we have an endometabolic mechanism to “clean ourselves out; intracellularly for our recapturing of said proteins/amino acids for the resequestering of our own reuse.

    This explains alot,….as related to our ability to fast for many days, weeks,…and even months when “food” is not available..or for our own ‘desire’ to readapt our inherent cellular mechanism back what may be stated as a “younger state”. But…

    There’s “no gain without pain” for most people. This appears to essentially be a good way to move into better health by individuals with the proper “notion, and then motivation and discipline”. In other words…..”go into a FASTing state,…and letting the bodies do their’ work to clean, rebuild other “sound cells”, and move onto a higher state of functioning.

    Finally, this pathway,….totally understood or not….appears to be of major interest to all athletes,….individuals trying to lose weight…or just get “reset to a better health standing”…without drugs or medical intervention; the costs, toxic side effects,…..time waste, or arguments with other medical individuals who have a vested interest into “the economic realities of massive drug interventions that deal only with symtomologies alone…and do nothing to reset our cell function”.

    Many drugs will become obsolete with this realization!

  • Sweden. A lot of the comments above are from Swedes and I would regard them as correct. I did not find this: although there is no “legal” lockdown, there are recommendations. Peolple follow them very well, I should think more than 80 % of the Swedes do. And about 20 % have confidence in the authorities. The idea has been to impose recommendations that can be kept FOR A VERY LONG TIME, withput people getting tired of them and being negliscient. That has worked. I am impressed by shop owners, restaurants, gyms, etc etc for all changes they have made to meet the new restrictions. More os less everything is open, but people do not go if they feel it is unsafe. So a lot of plexiglass to protect, marks on the floors in shots to help distancing, gym practice outdoors etc etc. Schools have been open ( and opened now again for the fall), but recommendations are that ALL that can, please work from home. Do not crowd buses and subways. Bus companies should put in extra buses to avoid crowding. Rather than having people wear masks, buses should run half empty. Walk, ride bike, do not travel if you do not have to, leave public transportation to people that absolutely must use it to get to work. And keeping the distance and hand washing is stressed. But for those above the age of 70, it is recommended not to socialize with children and grand childern at all they are out in society and may be infected. Not only peolpe in nursing homes should be protected, but ALL above 70. So that is a severe restriction, and people are following it. (Internet deliveries of food is surging). As soon as it was discovered that many of hte deaths were in nursing homes, an investigation was made to find new better ways to work. After that, we do not have any problems with nursing home at all any more. As you say, because we are still following the same rules, the steady decrease of deaths and ICU can be explained by some kind of immunity. We find no other explantion. As in other countries, we now find young people are not as strict. ( the 70+ are the best ) But that has not (yet at least) led to increase in mortality. School children do not seem to be sick to any large extent. There has been no mortality among the 1,7 million school children

  • I have been saying this for weeks. I know of about 10 people in the 79 104 year old range in nursing homes that have caught the virus and recovered with no symptoms. Their immune system has to be weak so the ONLY answer is they had a virus earlier in their lives that has given them protection.

  • Spot on dr bean! I think Sweden’s policy was correct for them. I’m not sure it would have worked in every country but for sure there is light at the end of the tunnel. I’ve suspected for a few months now just by studying the data myself but hearing the same theories from you makes it all the more comforting.

  • Dr. Kroemer is a well established scientist and also has published in purinergic signaling in HIV among many other topics. It is good to see him after reading many of his papers. Thank you for posting this video. Marc C. E. Wagner http://www.marccewagner.com/

  • Were I giving advice to the masses, I would be conservative. But I have no weight, I can point out: so, using mechanism and common sense alone, there are 2 glaring flaws in the current usa approach. Firstly, the USA population could have boosted their innate defense back in March, with a BCG campaign. Or the twiv interview with the WHO virologist, suggestion that the opv could protect America for 30 million dollars, with same result as BCG protection… The second mistake is that by becoming like the bubble boy, we are missing out on nature’s immunization micro exposure to a very low virus count, which could explain why social distancing/hygiene alone has very good results. Obviously, even not in a position of authority, and not conservative in advice, I can’t emphasize enough how diabetics, prediabetics, should wear n95 masks, lower their blood glucose, ban fructose and added sugar (likely industrial seed oils too), and keep up regular vitamin and mineral support. Exercise at right times is essential for normal blood sugar for many, as well. Unfortunately, medicine, and politics are 2 very different things. Every American should have a free consultation with a Drbeen educated doctor, evaluated for blood sugar, A1C, then educated on diet, prophylaxis and habits to minimize the risk of severe covid ride. Treatment needs to start on day 1 of symptoms. Most of this can be done through telemedicine.

  • Every time I heard DrBeen say: “Swedes didn’t change their behaviour.”, I thought; “Huh, what?”. Swedes change their behaviour a lot, going from winter to spring to summer.
    That’s because of the changing weather. The spreading of the virus can also be influenced by the weather. Vitamine D-levels also, because sun bathing is very popular in Sweden and exposing naked skin during spring.

  • I listened twice and rewound, several complex sections and was still left a bit confused at the end. But in another Dr. Patrick video, they noted even black coffee starts metabolic processing, so it isn’t truly fasting. Anyone comment on this distinction please?

  • You don’t get immunity by having covid, it doesn’t “just go away” it sticks around keeps making you sick in new creative ways and you continue to spread it when you feel good. Children are great at spreading viruses already so their asymptomatic spread capacity is professional level. So you doctors out there remember… you are as stupid as children who don’t listen to their mother… gargle salt water. How many more times will I repeat this before the medical community already agrees gargling salt water reduces virus particles in your mouth nose and throat. It makes wearing a mask more comfortable because you slow the increase of your own viral load. We are all carriers so if we do just one small, cheap, insignificant thing each day we make the whole world healthier. Gargle salt water.

  • @DrBeen I am working on Sweden, but I come to the collusion that comparison with adjacent countries, Norway, Denmark and Finland is required to see the full picture.

  • In any of the other forms which could indicate possible immunity… are there any documents, any reputable studies…. anything reputable as a source to do some estimate ranges on which each of them could be in a possible population? any extrapolation sources? It would be interesting to look at that.

  • Dr. Been No country or individual will let the virus take its’ natural course. Sweden is following a non stringent lock-down not as seen in Europe or Asia that showed a relative increase in cases compared to neighboring countries so in my opinion the cases will go up once other European countries enter to a second wave which will disperse the virus during travel or when the population relaxes measures instinctively taken and if the government makes additional eases on the directives………please tell us why the African continent is low on the no. of deaths. thanks

  • The case graph spiked when we got testing of everyone, probably that curve should look more like the death graph. We have probably evened out at the moment with partial herd immunity, 60% working from home and maximum 50 people gatherings. If everything went back to normal the spread would probably spike again.

  • As compared..please explain a rationale for China. It’s so hard to say agreed at all levels because the questions remaining.even if they had changed..it only procrastinated for hard hit areas. Once some lockdown were placed they too had better results. Then the restart had rumors of more spread. Idk.

  • Thanks Dr Been. Thought provoking. If we are kept locked down then how can we develop the T cell immunity?
    I need to go back and watch the videos again.

  • Brilliant insight, but a little dangerous because of the politics and all the people who want the problem to just disappear. We have tests for infections, and tests for antibodies, but no test for people who defeated the coronavirus using only the innate arm or helper T cells? Could we test them with a harmless coronavirus to see if their immune systems are adapted to it?

    Essentially, there are two paths we could take. Eradicate the virus from the planet completely. This is what the Chinese tried to do. Or, the virus spreads until herd immunity develops, then it stops spreading and may even disappear. When considering the second path, I think we have to recognize that people with serious illnesses or in nursing homes cannot really be isolated. We do not even put people with covid-19 in different hospitals. So although herd immunity may be the unavoidable end of the pandemic, the price will be the lives of many sick and frail people.

    The idea may even have some secret appeal to right-wingers who think that if people are homeless and dying in the street, it’s nature’s way and a necessary part of an efficient economy. The elderly and sick are not productive anymore, so why not kill them off? If I were living in a nursing home I would be very concerned about herd immunity.

  • QUESTION: Is single dose of Ivermectin is enough for prophylaxis or should be given on Day 1-730 as prophylaxis. Thank you.

  • Maybe the number of deaths are wrong.
    ’Corona deaths’ are persons who died with Coronavirus. They didn’t necessarily die from it.
    There’s a study in one of the swedish regions (Östra regionen) that suggest that 15% died directly from corona, 70% had other health issues that could have caused death, 15% didn’t die from corona.

  • Swedes made a self-regulated lock down that is still ongoing.
    Swedes have holidays in the summer and spend more time outdoors and the flu normally comes in the winter.
    Those who are bad at social distancing or have a vulnerable job first become immune, thus creating herd immunity faster, as long as self-regulation is ongoing.
    Now schools have opened and work has started again after summer, but we have not seen any increase in cases yet, despite extensive testing. However, we believe that immunity is unevenly distributed.
    The best data to use to see the spread of the virus in Sweden are hospital admissions. Mortality depends on how well the elderly are isolated from the virus. PCR testing was insufficient at the beginning of the pandemic, but you are admitted to hospital on the same assessment throughout the pandemic.
    https://www.svt.se/datajournalistik/corona-i-intensivvarden/ Google translate.

  • Indeed a very enlightening explapnation of very complex subject. now I begin to understand why in some occasions we tend lose appetite or avoid foods when we are not well.

  • Couldn’t disagree with you more Dr D, Sweden’s case rate when multiplied to equivalent UK population levels is daily 2400, the UK is around 1200. We know in the UK we are nowhere near herd immunity levels, and yet Sweden is experiencing double our new infection rate. If as you allege that they are well on the road to herd immunity, then why is their infection rat so much higher than a country that is nowhere near herd immunity. To me this is a mutually exclusive situation, especially when you consider population density is so much higher in the UK. It should be facilitating transmission

  • Thank you Dr, am just thinking of herd immunity is achieved we should have high no.of deaths shouldn’t we?but their no is reduced!

  • Sweden government links on schools, masks, economy, deaths, excess death above the all cause mortality line vs previous years and/or ILI seasons etc. For a condensed version of the data, the second link breaks it all down and gives links to the Sweden government health agency websites. I also sent a few interviews of Swedish head Epidemiologists/Doctors, like Chief Anders Tegnell, Johan Giesecke and Soo Aleman Sweden has…

    (1) Dense urban areas
    (2) Hard hit migrant population
    (3) Early infections in Stockholm
    (4) Stringent counting of #COVID deaths
    (5) Nursing homes that were unprotected

    https://www.folkhalsomyndigheten.se/the-public-health-agency-of-sweden/

    https://softwaredevelopmentperestroika.wordpress.com/2020/07/07/guest-blogger-haraldofw-all-you-ever-wanted-to-know-about-corona-sweden/

    https://softwaredevelopmentperestroika.wordpress.com/2020/07/19/covid-19-sweden-a-summary/

    https://www.folkhalsomyndigheten.se/the-public-health-agency-of-sweden/communicable-disease-control/covid-19/?exp=68218#_68218

    https://experience.arcgis.com/experience/09f821667ce64bf7be6f9f87457ed9aa

    https://youtu.be/bfN2JWifLCY

    https://youtu.be/xh9wso6bEAc

    https://youtu.be/CwQpg62Kflg

    https://finance.yahoo.com/news/swedish-companies-reap-benefits-country-000000203.html

    https://www.thelocal.se/20200805/what-does-swedens-gdp-drop-actually-tell-us-about-lockdown-and-the-economy/amp?_twitter_impression=true

    https://www.reuters.com/article/us-health-coronavirus-sweden-schools-idUSKCN24G2IS

    https://experience.arcgis.com/experience/09f821667ce64bf7be6f9f87457ed9aa

    https://www.folkhalsomyndigheten.se/the-public-health-agency-of-sweden/

  • You say you’re not a fan of Swedens strategy. Why is that? What do you feel they should have done differently? Do you think the U.S have a more effective strategy? I personally feel like Sweden failed in terms of elderly care homes (like many other countries/states), but over all ICU capacity was never exceeded. Most of the people who died were already very old and had a very short life expectancy already. I do sometimes feel like people are not properly taking in to account the damage lockdowns can have on over all public health, at some point the damage of a lockdown surely exceeds the benefits?

  • If there is herd immunity approaching (I think it is), remember as it affects Rt, Rt is also mediated by social behaviour (social distancing, masks etc) and seasonality.

  • Doctor, the reason that in Sweden cases and deaths reduced so much is due to two things herd immunity like you propose, but not completely, it is also creating a buffer between the pre symptomatic and the vulnerable, since only the pre symptomatic actually spread the virus. and the asymptomatic can only transmit virus that get attached to the parts of the body, hair, limbs and face it is by very far a good transmitter of the virus, so the buffer is created because people will tend to see more or less the same people as they go places, and this also helps to create a wall between the vulnerable by being exposed more and more to the asymptomatic people and since asymptomatic people do not reproduce the virus in themselves their connection to the infected pre symptomatic people result in no or transmission of the virus which result in great reduction of the statistics also. this wall can solve the infection without the 67% needed for complete herd immunity.

  • Dr John Campbell interviewed a Swedish physician a month or more ago. He said older people were not allowed to have supplemental oxygen so many died tragically. All they were allowed to have was morphine and sedatives. Hopefully this has changed. At that time there were public ads stating that use of supplemental oxygen was too dangerous…might explode or cause fires. Deliberate campaign to cast a doubt on the safety and value of using oxygen. That is what caused such a high death rate among the elderly.

  • I wish it were true that immunity is being reached, but in Mississippi they REDUCED testing by 33%. The government here wants to open everything. I do not trust that the very recent slightly lower numbers of detected infections in MS are a true reflection of reality, especially since deaths are staying at the same daily level.

  • With Sweden, I would add that they never really did the mask wearing, few wear them if at all, and they are out in about in shops, cafes restaurants and bars, and beaches/parks, so it should be spreading like crazy now if there isn’t any level of immunity blocking many from being infected.

  • I have some queries on Covid 19 antibody tests…

    1. Neutralizing antibody against which antigen…spike protein S1 or S2 or Nucleocapsid protein…

    2. How to differentiate binding IgG and neutralizing IgG with CLIA test….

    3. How the CLIA can determine the detected IgG antibodies are capable of Neutralizing SARS CoV2 without doing PRNT assay….

    Please enlighten me sir.
    Dr,Safi
    Nagercoil.India

  • A doctor friend of mine from Uruguay, Dr. Marysol Romero, MD, OBG-YN, told me that the Spanish flu destroyed itself by mutating itself into a weaker strain. Also, isn’t it true that every time the virus infects a person it gets a good beating from that person’s immune system and thus becomes weaker, and so if it exits that person to go infect another one, wouldn’t it be a weaker version of the very 1st viral infection that 1st attacked the person? If so, the virus is thankfully self defeating. Also as the word spreads of deaths and of people that get really sick, people are more careful to not catch the virus, and so there is less infection, and thus less infection detection. Couple that with the fact that the virus finds less people to infect because so many have already been infected and/or died.

  • I found this interview extremely interesting, esp., about the importance of autophagy in using the immune system in the long term suppression of a cancer.

  • Finland is kinda known as a nation of introverts, built in social distancing kinda. I don’t know if their neighbor Sweden has a similar population.

  • Sweden has NOT achieved herd immunity! There is NO SUCH THING as herd immunity! IT IS A MYTH! Everybody will DIE of COVID19 this fall and winter! Billions around the world will die! There is no stopping it! Sweden and Belarus will be the FIRST EXTINCT NATIONS! Swedes and Belarussians WILL BE the FIRST EXTINCT RACES!

  • .Since it has been difficult to identify doctors in the USA who will treat COVID-19 outpatients EARLY with treatment protocols proven effective in case experience, I am drafting a directory of such doctors and plan to post it on the web. Doctors in countries besides the USA also will be listed if that is useful. 

    My research indicates that Ivermectin based protocols are the most effective but have found few doctors in the USA prescribing IVM. 

    PLEASE PROVIDE ANY ADDITIONS TO THE LIST OR COMMENTS YOU MAY HAVE. (Formatting will be better; YouTube limits formatting.)

    Doctors Prescribing Outpatient Early COVID-19 Treatments (Updated 21Aug2020)

    Based on case experience, various combinations of Budesonide – nebulized (BUD) + Ivermectin (IVM) + Hydroxychloroquine (HCQ) + Doxycycline (DOX) + Azithromycin (AZM)  + Zinc + Supplements are effective for early (and sometimes later stage) treatment of COVID-19. 
    Primary drug is listed in parentheses. 
    THIS LIST IS NOT GUARANTEED TO BE ACCURATE. 

    ALABAMA: Dr. David Calderwood.
    CALIFORNIA: Dr. George C. Fareed (HCQ), Dr. Bob Hamilton (HCQ), Dr. Joseph Ladapo (HCQ), Dr. Donald C. Pompan(HCQ), Dr. Mobeen Syed (??). 
    FLORIDA: Dr. Michael M. Jacobs (HCQ), Dr. Juliana Cepelowicz Rajter (IVM), Dr. Jean-Jacques Rajter (IVM). 
    LOUISIANA: Dr. Lauren Mickey (IVM). 
    NEW YORK Dr. Vadimir Zelenko (HCQ). 
    TEXAS: Dr. Robin Armstrong (HCQ), Dr. Richard Bartlett (BUD), Dr. Stella Immanuel (HCQ), Dr. Ivette Lozano (HCQ), Dr. Brian Procter (HCQ), Dr. Sheila Schmidt (BUD)

  • Hey, Swedish here!
    This was one of the best presentations I have seen, on the Corona situation of Sweden! Very good:)

    The only thing I’d like to mention is that the rise in the curve at the red part of the “daily new cases” in Sweden was actually not an increase of cases, only massive increased testing. Since before June, they only tested people who became very sick. In the beginning of June, Swedish government decided to make testing free for everybody. That’s when I tested myself. They stated this at every daily press briefing for weeks on end, since foreign media made a big deal (and misunderstanding of it).

  • We have never had zero deathcases in sweden. We dont report cases over weekends. If you are saying that swedens nonstrategy was the right thing from the beginning,let me remind you that almost 6000 people paid the price for that. In this stage after the fact that alot of people died in vain,ofcourse some immunity has developed but mostly in the big cities,not the country as a whole.

  • If natural herd immunity is the end-game for some regions then what is the best epidemic-management policy moving forward? In the herd immunity scenario we know that the total cases to terminate the epidemic is roughly constant according to theory. Therefore you want the “minimum cost” to achieve the required total cases. The cost could be in lives lost, economic damage, or some combination. One policy would be to open schools. Children are low risk but high benefit in terms of growing the immune herd and their parents are lower risk than their grandparents who should be shielded for a time. By shifting the immune herd toward younger people we shift it away from the elderly and would therefore see lower total deaths. According to my calculation this also results in lower cumulative lost life-expectancy. So that’s one simple approach to lower cost but convincing fearful parents and politicians is not so easy.

  • Compare the numbers in NY with Sweden, Florida, and Louisiana. I believe Sweden has reached herd immunity with much lower numbers because they are exposed to more Coronaviruses every year than US states that are much further south and have much warmer climates.

    Therefor countries that have cold climates should all experience herd immunity sooner than those countries with warmer climates.

  • Add along this that in fact the corona or crown of the sun has to do with the understanding of energy reaction. Although it’s not exact in our terms or in blood the compared is real. Like a that of a thermo reactor of some sort. It’s true…the way it became conversation to understand what was a base for internal edu. Not by all public..true too

  • Ibuprofen became a concern after the inflammation attacking organs. Due the unknown reaction it was advised less helpful Feb or March..it can be a functional burden or make matters worse.

  • Does anybody eat chicken skin as fat macros? Cause I take out the skin but then eat avocado for my healthy fats, maybe if I eat the whole chicken with the skin the avocado isn’t necessary and I’ll save money

  • I’ve never understood how to count macros. It’s like math to me… I’m wondering if I eat too many healthy fats? Is there such a thing?
    I’m 41 years old. 120lbs. Athletic body type but have a pooch belly. Could that be from fats?

  • The truth is, I never tracked my calories nor macros. It might be important for many but it’s not necessary for me. As fitness and health conscious adults, we all know junk foods and high caloric foods. It doesn’t take us anything to avoid them or take them in a minimal amount. If you are conscious and discipline in the kitchen, coupled with a reasonable amount of exercise. You MUST loose weight and achieve your desired body goals. If I can do it without tracking any calories nor macros, then anyone can also. But if you have the resources and time to invest in tracking calories and macros. Then go for it. It might work for you.
    Great content Danny. Stay healthy everyone.

  • Parkensons patients need to monitor their BMI carefully. They may want to get with a nutritionist that works with marathon runners as parkensons uses in some cases use as running a half marathon daily.