Sucralose is protected and Scrumptious


Effect of Sucralose (Splenda) on the Microbiome

Video taken from the channel:


Ditch the Splenda ASAP. Here’s How Sucralose Is Destroying Your Gut Audio Article

Video taken from the channel: Bulletproof


Demystifying the myths surrounding artificial sweeteners

Video taken from the channel: Demystifying Medicine


Artificial Sweeteners and Gut Flora, Why I don’t consume Sucralose

Video taken from the channel: JonHealthandFitness


Always Safe | Always Effective | Always Delicious

Video taken from the channel: TruLabs


The Truth About Sucralose and Health

Video taken from the channel: Food Insight

Sucralose is a zero calorie artificial sweetener, and Splenda is the most common sucralose-based product.. Sucralose is made from sugar in. While the people SELLING natural remedies and using scare tactics to get you to buy their stuff, sucralose has been proven safe, has GRAS Status (Generally Recognized as Safe), and is delicious! In my opinion, it can help you cut many extra sugar calories from your diet without sacrificing taste, can alleviate blood sugar spikes and crashes, and can be a part of your daily diet. Sucralose—the no-calorie sugar substitute known as Splenda—has been found to cause a variety of harmful biological effects on the body, according to a new research review.

Overall, studies have shown that major artificial sweeteners like aspartame (used in Nutrasweet and Equal), saccharin (used in Sweet ‘N Low) and sucralose (used in Splenda) are perfectly safe for human consumption in moderate quantities. Are aspartame, saccharine, and sucralose keto? We don’t recommend them. Diacetyl Free. Diketone free.

No Sucralose. No oils. Delicious flavors. Our collection of safe nicotine salt liquids for your favorite pod device! Recommended device for use is the UWell Caliburn we have on our website.

Salt nicotine vape juice is available in 25mg and 45mg salt nicotine levels. Overall, the existing evidence on sucralose from human studies suggests that it is a safe sweetener with few side effects. Toxicity studies show that sucralose appears to be safe in humans, even at doses exceeding the recommended daily amount. Very high doses of sucralose have shown adverse effects on the gut microbiome in rodent studies.

Besides the potential effects listed above, there are actually more risk factors associated with sucralose including effects on gut bacteria and cause interactions with medications. However, sucralose has been deemed safe at a maximum intake of 5mg/kg body weight/day by the FDA, equivalent to 23 packets/day. Once it gets to the gut, sucralose goes largely unrecognized in the body as food — that’s why it has no calories.

The majority of people don’t absorb a significant. Artificial sweeteners like aspartame, sucralose, ace-K and saccharin have been debated for years in regard to their potentially damaging effects. While all of these sweeteners are technically “safe” and sugar-free, according to the Food and Drug Administration, they. Luckily, there are quite a few sweeteners found in nature that are actually good for your health. They are low in calories, low in fructose and taste very sweet.

Here are 4 natural sweeteners.

List of related literature:

Sucralose is safe, noncaloric and does not raise blood sugar.

“Dr. Atkins' New Diet Revolution” by C. D. C. Atkins
from Dr. Atkins’ New Diet Revolution
by C. D. C. Atkins
M. Evans, 2002

Sucralose or Splenda is not safe.

“Timeless Secrets of Health and Rejuvenation” by Andreas Moritz
from Timeless Secrets of Health and Rejuvenation
by Andreas Moritz
Ener-Chi Wellness Press, 2007

It is apparent that sucralose is not a safe sugar substitute.

“The Stevia Deception: The Hidden Dangers of Low-Calorie Sweeteners” by Bruce Fife
from The Stevia Deception: The Hidden Dangers of Low-Calorie Sweeteners
by Bruce Fife
Piccadilly Books, Limited, 2017

Extensive studies have been conducted on the safety of sucralose, and these have generally demonstrated that the substance is safe at the expected usage levels.

“Food Chemistry, Third Edition” by Owen R. Fennema
from Food Chemistry, Third Edition
by Owen R. Fennema
Taylor & Francis, 1996

Others are less convinced of its safety and suggest that, until more is known, pregnant women be cautious in their use of this sweetener.

“What to Expect When You're Expecting 4th Edition” by Heidi Murkoff, Sharon Mazel
from What to Expect When You’re Expecting 4th Edition
by Heidi Murkoff, Sharon Mazel
Simon & Schuster UK, 2010

Over 100 studies were submitted to the FDA showing that sucralose is not carcinogenic and does not cause genetic change, birth defects, brain or nerve damage, or other health risks.

“Linda Page's Healthy Healing: A Guide to Self-healing for Everyone” by Linda G. Rector-Page
from Linda Page’s Healthy Healing: A Guide to Self-healing for Everyone
by Linda G. Rector-Page
Traditional Wisdom, 2000

Sucralose is also noncariogenic.

“Food Additives” by A. Larry Branen, P. Michael Davidson, Seppo Salminen, John Thorngate
from Food Additives
by A. Larry Branen, P. Michael Davidson, et. al.
CRC Press, 2001

In comparison to aspartame, sucralose, and other artificial sweeteners, sugar alcohols are relatively safe.

“The Coconut Ketogenic Diet: Supercharge Your Metabolism, Revitalize Thyroid Function, and Lose Excess Weight” by Bruce Fife
from The Coconut Ketogenic Diet: Supercharge Your Metabolism, Revitalize Thyroid Function, and Lose Excess Weight
by Bruce Fife
Piccadilly Books, Limited, 2017

No health concerns have been reported with sucralose.

“Pediatric Dentistry” by M. S. Muthu, Shiva Kumar
from Pediatric Dentistry
by M. S. Muthu, Shiva Kumar
Elsevier Health Sciences, 2019

An overview ofthe safety of sucralose.

“Sweeteners and Sugar Alternatives in Food Technology” by Kay O'Donnell, Malcolm Kearsley
from Sweeteners and Sugar Alternatives in Food Technology
by Kay O’Donnell, Malcolm Kearsley
Wiley, 2012

Alexia Lewis RD

Registered Dietitian Nutritionist and Certified Heath Coach who believes life is better with science, humor, and beautiful, delicious, healthy food.

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  • What about lowcalorie sweeteners that are more natural like Stevia in the Raw which are taken directly from a plant, similarly to sugar but without the calories? Would that change gut bacteria or insulin resistance? Also, do the changes in gut bacteria cause the insulin resistance, and if so how? 
    I eat Stevia in the raw every day and am not sure if it has the same adverse effects.

  • Sucralose is poison. I’ve ate a fairly decent diet my entire life. 2 months ago I started getting really bad heart palpitations, headaches, light headedness, and awful anxiety. I couldn’t figure out what was going on. It was Mio water enhancer. I started drinking it all the time 6-8 glasses a day. Of course it contains sucralose. And if you do a simple google search on aspartame and see the top complaints you will find that my symptoms are described time and time again from other users who thank god figured out this was the cause. This stuff should be banned!

  • Where is the evidence that artificial sweeteners are safe? Did the companies making them carry out the study? Just use stevia instead if you want the sweet taste and there is no issue

  • How about Stevia, not artificial?
    Stevia is a sweetener and sugar substitute extracted from the leaves of the plant species Stevia rebaudiana. The active compounds of stevia are steviol.

  • Is there really any evidence that organic sugar in a 95% whole plant based diet has ANY ADVERSE HEALTH EFFECTS?!?!?! Perhaps a healthy alternative to sucralose IS sugar!

  • SPLENDA® is also the brand name for the ingredient sucralose. It is made through a patented, multi-step process that starts with sugar and converts it to a no calorie, non-carbohydrate sweetener. The process selectively replaces three hydrogen-oxygen groups on the sugar molecule with three chlorine atoms. Chlorine is a natural part of salt, which is found in many foods, like lettuce, tomatoes, mushrooms, melons, and peanut butter, and chlorine is added to most public water supplies. Chlorine is also a part of more complex molecules found in such things as lentils, peas, and potatoes. It is a part of daily life. In the case of sucralose, its addition converts sucrose to sucralose, which is essentially inert. The result is an exceptionally stable sweetener that tastes like sugar, but without sugar’s calories. Sucralose isn’t broken down for energy, and is not recognized by the body as a carbohydrate.

    The calorie and carbohydrate content for SPLENDA® No Calorie Sweetener, Packets and Granulated is as follows:

    SPLENDA® No Calorie Sweetener, Granulated
    1 teaspoon =  0.5 gm carbohydrate = 2 calories
    *1 teaspoon  has the sweetness of 1 teaspoon of sugar

    SPLENDA® No Calorie Sweetener, Packet
    1 packet =.9 gm of carbohydrate = 4 calories
    *1 packet has the sweetness of 2 teaspoons of sugar

    Per U.S. labeling laws, anything with less than 5 calories per serving, is properly labeled as “zero” or no-calorie.

    The calories and carbohydrates in SPLENDA® No Calorie Sweetener come from dextrose and/or maltodextrin, which are added for bulk. Sucralose, the sweetening ingredient in all SPLENDA® Sweetener Products, has no calories and is not a carbohydrate.

  • Thanks for the great information. Respectfully, though the forced affections of speech, the coached-sounding pace and…………. pregnant pauses are not doing you any favors, Doctor.

  • I recently became aware of that info and I decided to stop supplements and post-workout shakes that contain sucralose. Needless to say, 99% of what is on the market has it simply because the alternative artificial sweeteners are worst and the supplement manufacturers don’t even dare to use sugar to sweeten the shakes (still harmfull but way better) or keep them unsweetened. I have been consuming this poison for the past 3 months daily. No wonder my morning bowel movements are of bad quality.

  • I have fatty liver and am not supposed to drink sugar I just learned sucralose aka splenda is in my kool aid squeeze water enhancer. It makes me poop mushy everyday sometimes twice a day. Guess ill go back to v8.

  • I’m not going to say this presentation is incorrect, but like is suggested in the video, correlation is not causation. During the same periods, other changes were occurring in processed foods, such as increased use of HFCS (in many cases, hidden) and increased glyphosate residues (from use of Roundup in agriculture), along with many folks switching to newly popular dietary approaches. Further, there are many habits that can harm good gut flora and enhance the bad kind.

  • I have too eat a lot of sucralose everyday, and I have crohn’s disease in my family, so how can I minimize the negative effects of it?

  • Frases like “massive amounts, small amounts” are relative terms. Is 2 packets of sucralose a lot? How do you define massive amounts? Five packets?.. 10?? Being a man of sciense you neede to be more specific. Lets see the data. Please do not use vague terms. If massive is 20 packs of sucralose I’de agree. Who would do that anyway? All I’m saying is if you where more specific you would be more credible.

  • I’m doing omad and just bought a schweppes sugarless apple (contains sucralose), first thing before drinking of course is to come to nutritionfacts and search for effects of sucralose. Thanks again doc, I won’t be opening this bottle!

  • ??
    He cites a study that looks at saccharine, aspartame, and sucralose. He then says there were negative effects found for saccharine and aspartame, but doesn’t mention sucralose. He then generalizes that all artificial sweeteners are probably bad for gut health. Why is the title about Splenda when sucralose wasn’t found to have negative effects in humans at normal doses?

  • Guys who’s going to gym and having supplements if you check the ingredients you will see sucralose in there, unfortunately. So better get your supplements unflavored

  • While your info is enlightening, your voice however is IRRITATING as hell…If you have a speech impediment, please pardon and ignore my comment…

  • I suggest people tough it out reduce the usage of sweeteners little by little. However, when you want to use a sweetner which of: sucralose, aspartame, stevia, xylitol, sorbitol, licorice, anise, cinamon, allspice, nutmeg, lactose, maltose, sugar, is recommended? Is there an ideal balance? You can get cheap AR glasses by using a cellphone, maybe, if we get hundreds of thousands of people to photograph their meals we then use cheap Indian labor to turn those photos into data and then mine the data.

  • It doesn’t seem NF was very honest when doing this research. Unnatural vegan exposes this pretty well in her response. Makes you wonder, how honest are the rest of these videos?

  • Thank you for interpreting these important studies for us! I’m starting the Slim Fast diet today for a month and vlogging about it. It’s an experiment because I’m a personal trainer, and want to see what happens. I’m concerned about the Splenda, fat, and other ingredients in this product. I’m subbed and liking your channel!

  • Could you do a video on IMOs, like they are found in vitafibre?
    So, if I used pure VitaFibre (Isomalto-Oligosaccharides), not by taking
    QuestBars (I know there is a lot of junk in there), but by using the
    syrup in baking, would it be healthy?
    Thank you, it is much appreciated!

  • The human microbiome is made up of between 40-100 trillion micro organisms – which include bacteria, viruses, fungi, protozoa and other organisms; Our microbiome contains hundreds of different bacterial species – and over 3 million genes. our gut microbiome has 150 times more genes than the human body does. SOURCE:

    Sucralose was approved by the FDA as a tabletop sweetener in 1998, followed by approval as a general purpose sweetener in 1999. SOURCE:

    In 2015, an estimated 1.3% of US adults (3 million) reported being diagnosed with IBD (either Crohn’s disease or ulcerative colitis).1 This was a large increase from 1999 (0.9% or 2 million adults). SOURCE: CDC

    It is not unreasonable to suspect that some of the Hundreds of Different organisms in our Gut Biome may have the Enzymatic and Fermentation ability needed to break the bond of the Chlorine Atoms from the Sugar Molecules, releasing the Sugar for them to consume, and releasing the Chlorine into the Sucralose Consumers Bowel.

  • Don’t believe commercial nutrition companies. They are all liars who publish biased researches which encourage usage of their own sweeteners or other nuritaion materials that they sell. Sucralose has no effect if you take them in moderate daily quantities. 1 gram of sucralose per day is safe and enough for 1 liter of drink especially acid drink like lemon and soda. 1 gram of saccharine daily (in addition to sucralose) is also 100 percent safe. I drink daily 1 litter of soda+lemon juice (extracted by me from lemons excelent taste better than commercial lemmon extract); also, in addition I drink daily 1 litter of milk + coffe, the soda is sweetened by 0.75 gram sucralose, the milk + coffee is sweetened daily by 0.85 gram of saccharin (together 2 litters of drink daily which clean my blood of urine acid). Everything is fine. Don’t touch stevia, most preparations of stivia contain poisons which accumulate in your body and not not disposed off by the body. Commercial nuritions won’t tell you that stevia is poisoning because they get rich by selling you stivia preparations (they sell you stevia for high price but the preparation is very cheap).

  • Thanks for your thoughts and findings on this. Im definitely going to check out those other videos when I have time. Being someone who reviews energy drinks, Sucralose is one of the only ingredients people seem to be able to complain about (besides sugar) without a lot of evidence (as you mentioned) to support it…since studies are still ongoing. But it is something I am trying to stay educated on as well so I can provide accurate information. Even though the FDA approves it, doesnt mean that cant be changed. So, in your opinion, if an energy drink with sucralose also uses green tea extract as its base, do you think the polyphenols and antimicrobial properties of green tea may help offset the gut health issues sucralose may cause?

  • Can we just make, “Here’s What Swayze Thinks Before Being Aware Of The Research” the new motto for Unnatural Vegan’s channel?

    Though don’t pay attention to me, because I’m probably anti-science for disagreeing with her.

  • hell yeah i always wanted to give up soda, energy drinks, and diet soda. now i can not give up alcohol! i just gotta drop this shit instead. diet coke taste like shit anyhow

  • The FDA works for big companies not the citizens; they banned cheap drugs from other developed countries so that drug companies get more money! Coca-Cola & other sweet companies still teaches the weight gain is caused by calories-in-calories-out without telling people how those calories change gut microbes, hormonal response, effect on apetite, etc…

  • I suffer from recurrent bouts of IBS. I’ve never had any issues with Equal(not that I use artificial sweeteners that often), however, after consuming half a portion of a Dunkin Donuts Lite Iced Late, I became extremely bloated. I wound up being stuck on a brat diet for the next two to three months. FYI, I’ve found that peppermint capsules and L glutamine seem to help me heal from IBS outbreaks.

  • Unnatural vegan has destroyed this narrative that the Fake news and videos like these has created in public perception. Her analysis is very fact based and significantly substantiated unlike this cherry picked position.

  • This makes sense. The reason it tastes sweet is because it stimulates the same sensory nerves that sugar does, and how ELSE does your body know to “prepare for sugar incoming!!” if not by nervous system stimulation? So of COURSE there’s an insulin spike. And when your insulin shows up to a sugar party when there’s no sugar to be found, it PROFOUNDLY influences your subliminal foraging behaviors until you find actual sugar to fillthat void. Sucralose is not directly putting more sugar into a person’s blood stream, as the data shows the correlation is there but there’s no study where one party of individuals in a metabolic ward are fed it with no access to carbohydrate rich food, another party is fed it but HAS access to more carbs elsewhere, and a control group is not fed it but has access to carbs if they so choose. My hypothesis is that this is a behavioral manifestation.

  • It might have something to do with the disease of acid reflux too. I used to have really bad acid reflux but since I changed my diet to avoid artificial chemicals, process foods and junk foods I don’t have it anymore.

  • Sucralose of any amount?

    There’s this product called zipfizz and they use small amounts of sucralose. I reached out to the manufacturer and they said they use small amounts of it combined with xylitol. My OMAD right now consists of raw milk (to help the microbiome) with bone broth powder.

    Any opinions?

  • A threshold or suggested acceptable amount specifically of sucralose would be very helpful. Products like Huel are vegan but contain sucralose to be more palatable (non sucralose versions I find I did not keep up the breakfast habit).

  • a friend of mine was told not to use Splenda, by his Dr. due to type 2 Diabetes. She recommended him using stevia instead. Is there a difference? Thank you.

  • Why didnt you bring up the part saying that normal weight people who had splenda reguraly didnt have any effects to their insulin?

  • Got to love the graphs at 1:30. Sucralose causes 20% more of an insulin response than water…. The fact that the comparison is with water and the graphs show that even water has an insulin response makes me unconcerned. If water has an insulin response, there’s nothing we can consume that doesn’t…

    The gut bacteria modification is more interesting though, but it needs more study, as the study here uses a small number of people and shows quite a modest change in both blood glucose and gut bacteria. Still, worthy of larger studies for sure.

    The biggest impact on obesity still remains caloric excess though. If Sucralose can cut hundreds calories out of your caloric intake a day, it’s still the lesser of two evils in societies where obesity is fast becoming the number one killer.

  • Eat food that’s alive!!!!!! Yogurt, kafir, chees, beer (non-alcoholic), vine, pickles, quality bread etc… anything fermented to keep up the gut bacteria, specially for older person!
    Processed foods are pasteurized, salted, radiation treated to kill off bacteria, incl. good bacteria to gain shelf life at the store, not healthy for digestion, specially milk.
    Eat fresh foods as much as possible, like live fish at the market etc…!

  • As with most of the comments people haev made here, I too had a similar experience with sucralose. I would take a BCAA flavored powder with my water and drink about a gallon a day and eventually had bloating, cramping and crappy bowel movements. “See what I did there!?” Also I had worsening depression and anxiety for no apparent reason. Till recently I discovered the side effects of sucralose and the damage it does to the gut.

  • Wait, the results came from the other two not sucralose. Why the misleading title? Aspartame was the one that showed the horrible results not sucralose.

  • What are you guys all asking about this Stevia crap? I don’t need anyone to do studies on it just go watch Breaking Bad and you’ll never try it again.

  • A lot of flawed correlations here. And 2nd half of this video is directed mostly at Aspartame, and then lumps Splenda in with “all artificial sweeteners in general.” Personally, I have been using Splenda in my mid-day coffee (2 envelopes) for 9-10 years with no side effects. And I use it because regular sugar bothers my teeth. Splenda does not. I am 70 years old, slim, mostly vegetarian diet, and relatively good health. And absolutely NO digestive problems.

  • One of my outtakes here is to eat more foods the way nature, naturally, provides them. Stevia is probably the healthiest sweetener alternative, especially for diabetics, and it is plant-based and all natural. I recommend people get more probiotics in their diet, whether it is pickled or fermented foods, sauerkraut, or supplements, etcetera because there is so much… stuff, in our drinks and foods nowadays and taking probiotics help to promote healthy gut flora that will help the gut function better. The gut is a very important part to overall health and is also involved with the immune system.

  • Thank you! I gave up Sucralose and Aspartame 3 weeks ago after 34 years of daily ingestion of artificial sweeteners. I have had to take smaller doses of insulin in order to avoid hypoglycemic attacks. Overall I am feeling calmer. It seems that the packets of Splenda in my daily 3 cups of coffee and 3 diet sodas were also having a negative effect on my mood.

  • I recently started drinking Coke Zero and liked it overall, but noticed that I get strong stomach aches after a few weeks of drinking it on a regular basis (whole can after meal). So I searched for Greger’s advice and found this great video! Next step is to take all those cans from my refrigerator and put them away, and go back to the water that I’m used to drinking (and maybe find an alternative, healthier, carbonated drink).

  • Aspartame has 10%of it’s content is methanol used in windshield washer liquid and a lot of floor products to finish wood floors… and it says on my 5 galons to wear a mask and gloves when you manipulate it!

  • Im on keto and i was eating carb balance mission tortillas, atkins bars for a treat along with drinking ice sparking water all of which have sucralose. I was fine at first then digestive problems, heartburn and crippling fatigue hit me out of nowhere. I noticed i was bloated and could not digest anything because i would throw up maybe 5 or 6 hours later and my food would still be in my gut. I didnt know what was wrong with me and i shouldve went straight to the doctor. I put my symptoms in a search and i dont know how i found the info out about sucralose but i thank Jesus i saw it. Im still recovering with probiotics and eating no processed foods. Ive learned my lesson now to always read the label and keep myself informed.

  • ATP Lab also has an interesting perspective on this matter.

  • Now watch Unnatural Vegan response to this
    I liked her response too

    we do not need sugar of any kind

    I Like Doctor Michael Greger option better reduce both

  • Sucralose has a basic ph. 12. That’s too alkaline. Sucralose also affects cp450 in the liver. When you eat sucralose your body doesn’t know what to do with chlorine atoms. It provokes anxiety. And manufacturers are adding sucralose to weight gainers? How do you gain if you are anxious?
    Note to manufacturers: if you use sucralose I will ban your product forever. I am not supporting your stupid product with proven bad short term effects. If I need protein I will eat eggs or fish. No money to sucralose.

  • Recently (in the past few weeks) I have sharply increased my intake of Sucralose from consuming things like sugar-free syrups and adding it to my coffee. Now, I’m noticing more and more that come evening time I get very gassy and my stomach rumbles more than usual, sometimes get some sort of diarrhea. Does this have to do with my increased Sucralose intake ruining my gut microbiome? Is it okay to still consume Sucralose but just in smaller amounts and more infrequently?

  • In some ways, this is rather depressing. If we cannot have sweeteners or sugar, does that mean never tasting anything sweet ever again? This is a little too close to the Atkins position sweet bad, greasy, meaty, salty good for my liking. Of course, often times cravings for sweet tasting things are driven by glucose/glycogen availability in our bodies rather than our taste buds.