This a product review of High Performance Nutrition’s PA(7)… PA(7) is a strength enhancer fueled by Phosphatidic acid, which is DERIVED FROM PLANTS ��…it basically BOOSTS PROTEIN SYNTHESIS!. ••Grab some today!! ➡️ https://hpnsupplements.com/products/pa7-mediator-mtor-elevation. ••✅ CHECK OUT MY PERSONAL YOUTUBE ACCOUNT ➡️ https://m.youtube.com/channel/UC4IZyQL9qW-YCe0AIt1wG0g. ••✅Check out my Instagram Page for daily content ➡️ https://www.instagram.com/bigbagkt/. ••✅Check out High Performance Nutrition on Instagram ➡️ https://instagram.com/highperformancenutrition?igshid=1hw69zoch3qm4.. ••✅Also check out my guy Sean Torbati on Instagram ➡️ https://instagram.com/seantorbati?igshid=9h1plkg2180w
Phosphatidic Acid (PA) is known as Mediator, owned by Chemi Nutra.. Two studies have evaluated their effects on lean body mass and strength gains.. The two supplements (to date) that use Mediator branded Phosphatidic Acid are Biotest Micro-PA and Cutler Nutrition King.. References: [1] Phosphatidic acid supplementation increases skeletal muscle hypertrophy and strength http://www.jissn.com/content/10/S1/P13. [2] Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men http://www.jissn.com/content/9/1/47
The concepts of Muscle Protein Synthesis (MPS) and Muscle Protein Breakdown (MPB) are well known among avid athletes. It is the interplay between the two that determines if muscle is gained or lost. Recently it was discovered that orally ingested Phosphatidic Acid (PA), when accompanied with mechanical stress on muscle and adequate protein intake, significantly activates the Mammalian Target of Rapamycin (mTOR) signaling pathway. mTOR regulates protein synthesis, whereby ingested protein is translated into new muscle. That’s MPS. New scientific evidence suggests that PA may even reduce MPB. Mediator® Phosphatidic Acid (PA), our branded and patented ingredient compound, was demonstrated in a university study to provide double the muscle mass gain, increased strength, and double the fat mass loss in individuals engaged in weight bearing exercise and who consumed adequate protein. The science supporting Phosphatidic Acid relates to signaling by the mechanism known as the mammalian target of rapamycin (mTOR), which scientists believe is necessary for mechanical load-induced growth of skeletal muscle (muscular hypertrophy) and consequent strength gain. Many published studies indicate that the lipid messenger PA plays a critical role in this mechanical activation of mTOR signaling, and thus mTOR is currently a hot button of research. To date, we have conducted a vast amount of research validating Mediator® Phosphatidic Acid (PA) as safe and efficacious. In addition, PA is naturally found in small amounts in foods, and it is a legal dietary supplement ingredient and is not a banned substance. Two published research studies prove that the consumption of Mediator® Phosphatidic Acid, combined with resistance exercise, appears to have a positive benefit on strength improvement and muscle mass development in young subjects. The first study showed that subjects ingesting PA demonstrated a 12.7% increase in squat strength and a 2.6% increase in lean body mass (LBM), while subjects consuming the placebo showed a 9.3% improvement in squat strength and a 0.1% change in LBM. The second study found that subjects consuming Mediator® PA saw double the muscle mass gain, increased strength, and double the fat mass loss compared to the individuals consuming the placebo. 11 BRAVO contains 750mg of Mediator…Let the GAINS begin! Shop Our Website: https://redcon1.com/. Join The Tier Operator Program: https://TierOperator.com. Become a Redcon1 Alpha Team™ Member: https://alphateam.com. *Interact With Us On Social Media*. Instagramhttps://www.instagram.com/redcon1/. Facebookhttps://www.facebook.com/redcon1official. Twitterhttps://twitter.com/redcon1official. Website https://redcon1.com/. Call us about our brand and supplements: 1-855-REDCON1. Available 9PM EST to 5 PM EST Monday Through Friday!
Phosphatidic Acid Unleash Untapped Anabolic Potential! — Tiger Fitness. Phosphatidic acid is a researched-backed ingredient that helps with strength output, body recomposition, and stress reduction. Phosphatidic acid is a researched-backed ingredient that helps with strength output, body recomposition, and stress reduction. Menu.
Phosphatidic Acid Benefits Phosphatidic acid is responsible for muscle recovery following intense exercise.* This is due to its ability to activate mammalian target of rapamycin (mTOR). [3,4] The mTOR pathway is responsible for the regulation of cell growth, cell motility, cell survival, and protein synthesis. Phosphatidic acid is a supplement that’s been proven to help increase muscle mass throughout the body, and it seems to have an affinity for helping people build strength in their legs. None of the subjects who were studied seemed to report any short term negative side effects from taking PA, so there’s reason to believe that it’s relatively safe to consume – at least in the short term. Yes, phosphatidic acid is very safe for women to use. Phosphatidic is non hormonal, all natural, and will not affect levels of testosterone, estrogen, or any other hormone.
It enhances muscle growth by stimulating the mTOR pathway in the body, not by increasing levels of anabolic hormones. Best Form of Phosphatidic Acid. Phosphatidic acid (PA) is a diacyl-glycerophospholipid that acts as a signaling molecule in numerous cellular processes. Recently, PA has been proposed to stimulate skeletal muscle protein accretion, but mechanistic studies are lacking.
Furthermore, it is unknown whether co-ingesting PA with other leucine-containing ingredients can enhance intramuscular anabolic signaling mechanisms. Phosphatidic acid supplement’s unique angle or capability lies in its supposed ability to activate mTORC1 (mammalian target of rapamycin complex 1) –mTORC1 is a key muscle building activator that helps in muscle protein synthesis, resulting in increased muscle gainin the body system, resulting in faster, lean muscle building. Chemi Nutra’s branded, thoroughly researched, Mediator® Phosphatidic Acid (PA) ingredient compound, when orally ingested, can provide significantly more muscle mass, increased strength, and reduced fat mass, when adequate amounts of protein are administered within the anabolic window, to.
Phosphatidic Acid. Phosphatidic Acid, which we will lovingly call PA for this article, is one cool molecule. It does a lot of really important things in the body, but the one I care about is that it is a well-known activator of mTOR. This means PA has some serious potential for aiding in muscle growth. Hey guys, I know it’s a beaten topic but what is the opinion on PA for lean gains?
We have this study from JR Hoffman in 2012 that should prove PA is a good natty anabolic as resistance trained men showed increases of 2-3% LBM. Thanks to the ongoing research in the field of sports nutrition, scientists might have just discovered the next anabolic breakthrough: phosphatidic acid (PA). PA, chemical structure 1,2-diacyl-sn-glycero-3-phosphate, is a type of phospholipid integral to the structure of cell membranes.
List of related literature:
Thus, n3 fatty acids not only act competitively with cyclooxygenase substrates to reduce PG levels, but n-3 fatty acids exhibit a high requirement for hydroperoxide activator, an in vivo level that may normally be insufficient to promote rapid PG synthesis.
from Nutritional Oncology by David Heber, George L. Blackburn, et. al. Elsevier Science, 2011
However, retinoic acid is not the endogenous ZPA signal because transgenic mice containing a retinoic acid reporter (consisting of a retinoic acid response element linked to lacZ) do not show a gradient of retinoic acid, or indeed any retinoic acid activity at all, in the limb bud itself.
No post-translational modifications of the a-amino acids without side chain functional groups, i.e. alanine, glycine, isoleucine, leucine, and valine, have been reported.
Since the late 1970s, enzymatic hydrolysis of pretreated biomass with cellulases has proven to be an effective alternative to strong acids, minimizing production of inhibitors during the saccharification stage.
Modifying this analog to contain 1bhydroxymethyl and dimethyl groups at carbons 26 and 27 enhanced transcriptional activity, increased the stability of the VDR to proteolysis and reduced the dissociation rate.
from Vitamin D: Two-Volume Set by David Feldman, J. Wesley Pike, John S. Adams Elsevier Science, 2011
Interest in the fatty acid amides increased dramatically with the discovery of N-arachidonoylethanolamine (anandamide) as an endogenous brain cannabinoid receptor ligand (Devane et al., 1992) with the field further expanding with the identification of oleamide, a sleep inducing fatty acid amide, in
The amount of arachidonic acid, which is the central bioactive lipid in the anabolic process, liberated will largely control what occurs during this phase.
from Anabolics by William Llewellyn Molecular Nutrition, LLC, 2011
The role of these metabolites and related compounds in the regulation of endogenous levels of jasmonic acid is unclear.
It has been described as synergy supplied by the application of exogenous ketone and beta-hydroxybutyrate in combination with SCFA butyrate in the context of cellular and physiological outcomes (Cavaleri and Bashar 2018).
Does Custokebon Secrets (search on google) help me lost crazy amounts of fat? I see a lot of people keep on speaking about this popular lose weight diet plan.
Hello! I want to ask you… I cannot swallow capsule. Can I open the capsule and put it in water then drink it? Will that harm the benefit of the product? Is it save to do that?
This product has the Phosphatidic Acid Fearn Natural Foods Lecithin Granules, 16 Ounce
Serving Size: 2 level Tablespoons (15 g) Servings Per Container: 30 Amount Per Serving % Daily Value Calories 110 Calories from Fat 72 Total Fat 8 g 12% Saturated Fat 2 g 10% Trans Fat 0 g Monounsaturated 1 g Polyunsaturated 5 g Cholesterol 0 g Sodium 2 mg 0% Total Carbohydrates less than 1 g 0% Protein 0 g Calcium 21 mg 0% Iron 1 mg 6% Calories per gram: Fat 9 · Carbohydrates 0 · Protein 0 Percent Daily Values are based on a 2,000 calorie diet. Choline 450 mg * Linoleic Acid 4350 mg * Linolenic Acid 900 mg * Phosphatidylcholine 3450 mg * Phosphatidylethanolamine 3000 mg * Phosphatidylinositol 2100 mg * Phosphatidic Acid 1200 mg * Phosphorus 450 mg * Potassium 240 mg * Vitamin E 1 IU ** Thiamine ** Riboflavin ** Niacin ** Vitamin B12 ** Folic Acid ** *Daily Value Not Established. **Contains less than 2% of the U.S. RDA of these nutrients
How did phosphatidic acid work out for you? I can’t find your follow up video. Also, have you ever tried ursolic acid? I think the latter is part of the ‘calorie-restriction mimetic’ family, i.e. resveratrol. Like resveratrol, it is HEAVILY hyped but has little to no clinical data. Your views? (in addition to your results with PA)?
2 tablespoons of Fearn Soy Lecithin granules gets you Phosphatidic Acid 1,200 mg and Phosphatidylserine at around 800 900 mg for less than $10. 30 servings if on a limited budget. Old school bodybuilders have been using for decades. #helpYOUgetGAINS
I like how you incorporated scientific evidence and studies in your video. I am an undergrad in science and was able to relate and comprehend the terms you used. Definitely going to purchase PA and give it a go.
Does Custokebon Secrets (search on google) help me lost crazy amounts of fat? I see a lot of people keep on speaking about this popular lose weight diet plan.
Hello! I want to ask you… I cannot swallow capsule. Can I open the capsule and put it in water then drink it? Will that harm the benefit of the product? Is it save to do that?
Will it boost appetite for us who need to eat more or is halo better for it? I am on trt btw dont start telling me stack it with a test booster..:p
This product has the Phosphatidic Acid Fearn Natural Foods Lecithin Granules, 16 Ounce
Serving Size: 2 level Tablespoons (15 g)
Servings Per Container: 30
Amount Per Serving % Daily Value
Calories 110
Calories from Fat 72
Total Fat 8 g 12%
Saturated Fat 2 g 10%
Trans Fat 0 g
Monounsaturated 1 g
Polyunsaturated 5 g
Cholesterol 0 g
Sodium 2 mg 0%
Total Carbohydrates less than 1 g 0%
Protein 0 g
Calcium 21 mg 0%
Iron 1 mg 6%
Calories per gram: Fat 9 · Carbohydrates 0 · Protein 0
Percent Daily Values are based on a 2,000 calorie diet.
Choline 450 mg *
Linoleic Acid 4350 mg *
Linolenic Acid 900 mg *
Phosphatidylcholine 3450 mg *
Phosphatidylethanolamine 3000 mg *
Phosphatidylinositol 2100 mg *
Phosphatidic Acid 1200 mg *
Phosphorus 450 mg *
Potassium 240 mg *
Vitamin E 1 IU **
Thiamine **
Riboflavin **
Niacin **
Vitamin B12 **
Folic Acid **
*Daily Value Not Established.
**Contains less than 2% of the U.S. RDA of these nutrients
http://www.amazon.com/Fearn-Natural-Foods-Lecithin-Granules/dp/B00014FCRQ/ref=sr_1_1?ie=UTF8&qid=1424824274&sr=8-1&keywords=Lecithin+Granules
How did phosphatidic acid work out for you? I can’t find your follow up video. Also, have you ever tried ursolic acid? I think the latter is part of the ‘calorie-restriction mimetic’ family, i.e. resveratrol. Like resveratrol, it is HEAVILY hyped but has little to no clinical data. Your views? (in addition to your results with PA)?
Ben, we need the updates so we can get them up on our post here with the latest research:
https://blog.priceplow.com/phosphatidic-acid
And yeah, +1 for the Fearn Granules for sure!!!
2 tablespoons of Fearn Soy Lecithin granules gets you Phosphatidic Acid 1,200 mg and Phosphatidylserine at around 800 900 mg for less than $10. 30 servings if on a limited budget. Old school bodybuilders have been using for decades. #helpYOUgetGAINS
I like how you incorporated scientific evidence and studies in your video. I am an undergrad in science and was able to relate and comprehend the terms you used. Definitely going to purchase PA and give it a go.