Creatine Nitrate and Nitrate Salts for Intense Muscle Pumps


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Nitrates: The Freaky-Intense King of Muscle Pumps? Unless you have been living under a rock for the last three or four years, you likely know that amino acids nitrate salts (and creatine nitrate) are among the hottest new legal dietary ingredients in the sports nutrition industry. NS CN is the purest Creatine Nitrate available with proven purity certificates of analysis.

NSCN is the most powerful non-stimulant pre workout ingredient we have ever found. It combines the Nitric Oxide exploding pumps from food nitrates while being chemically bound to Creatine. One of the more popular organic nitrates out now is creatine nitrate (CrN).

Creatine nitrate is prepared the same way that arginine nitrate is, forming the same salt molecule that dissociates in water into creatine and nitrate ions. Creatine is the most widely studied supplement on the market, whose benefits are unquestioned in sports nutrition and performance. Cellucor CN3 uses creatine nitrate to give you insane pump and intense power to muscle through your workout and get you amazing results.

In other words, supplementation with creatine nitrate helps athletes perform more work with greater power and velocity while simultaneously reducing the amount of effort expended. Of course, I’d be remiss not to mention one other major aesthetic benefit to supplementing with creatine nitrate: bigger muscle pumps!Creatine Nitrate is a bonded hybrid of Creatine 67% and Nitrate 33%. This form of creatine is up to 10 times more soluble than Creatine Monohydrate meaning less is needed. Creatine is one of the most researched nutritional supplements on the market used by bodybuilders and endurance athletes alike.

One thing that creatine nitrate does offer is an advantage for bodybuilders over the standard creatine monohydrate is that it is attached to a nitrate group. Nitrate, or nitrogen atoms, is what helps the increase in oxygen levels in the bloodstream, which allows for a significantly greater pump. The optimal dosage of nitrate supplementation tends to be 0.1-0.2mmol/kg (or 6.4-12.8mg/kg), which is the range of: 440-870mg for a 150lb person. 580-1,160mg for a 200lb person. 730-1,450mg for a 250lb person.

Supplementation of nitrates via beetroot is equally feasible, and beetroot itself is dosed according to its nitrate content. Creatine nitrate is one of the newer supplement forms showing up in pre-workouts. Manufacturers claim that by binding the creatine molecule to a nitrate molecule, people will receive equal benefits from a smaller dose of creatine nitrate compared to creatine monohydrate.

Creatine Nitrate is Creatine Monohydrate bound to a Nitrate salt. Nitrates do aid in the process of N.O. production, therefore it may help you achieve a better pump/vascularity. It is also slightly diuretic, which is what she may have meant by ‘holding less water’.

The main goal of Creatine is to retain water in your muscles, anyway.

List of related literature:

Other studies have also reported an additive or synergistic effects of highȬintensity intermittent exercise, endurance exercise, or resistance training when nitrate supplementation is combined with sodium phosphate [151], caffeine [311], or creatine [306], respectively.

“Essentials of Exercise & Sport Nutrition: Science to Practice” by Richard B. Kreider PhD FACSM FISSN FNAK
from Essentials of Exercise & Sport Nutrition: Science to Practice
by Richard B. Kreider PhD FACSM FISSN FNAK
Lulu Publishing Services, 2019

Another possible benefit of creatine supplementation is muscle glycogen-sparing during high-intensity intermittent exercise (Roschel et al 2010) and increased muscle glycogen accumulation (Hickner et al 2010), although not all evidence supports this theory (Rico-Sanz et al 2008).

“Herbs and Natural Supplements, Volume 2: An Evidence-Based Guide” by Lesley Braun, Marc Cohen
from Herbs and Natural Supplements, Volume 2: An Evidence-Based Guide
by Lesley Braun, Marc Cohen
Elsevier Health Sciences, 2015

It had been proposed that supplementary creatine increases water retention and plasma volume of horses, but 25g creatine monohydrate given twice daily had no effect on maximal treadmill performance of Standardbred trotters, as expressed by muscle metabolic activity and total blood volume (Schuback et al. 2000).

“Equine Nutrition and Feeding” by David Frape
from Equine Nutrition and Feeding
by David Frape
Wiley, 2013

The potential benefits include increased muscle protein synthesis, increased glycogen synthesis, and free fatty acid availability,152 but in contrast to GH, IGF1 is not lipolytic.

“Williams Textbook of Endocrinology E-Book” by Shlomo Melmed, Ronald Koenig, Clifford Rosen, Richard Auchus, Allison Goldfine
from Williams Textbook of Endocrinology E-Book
by Shlomo Melmed, Ronald Koenig, et. al.
Elsevier Health Sciences, 2019

creatine in marine invertebrates.

“Research Grants Index” by National Institutes of Health (U.S.). Division of Research Grants
from Research Grants Index
by National Institutes of Health (U.S.). Division of Research Grants
U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, Division of Research Grants, 1971

Another benefit of creatine that may be key is cellular hydration.

“Textbook of Natural Medicine E-Book” by Joseph E. Pizzorno, Michael T. Murray
from Textbook of Natural Medicine E-Book
by Joseph E. Pizzorno, Michael T. Murray
Elsevier Health Sciences, 2012

Nitrate supplementation effectively enhances exercise performance in untrained or moderately trained subjects, but the limited data indicate that this affect is not seen in endurance-trained athletes.

“Nutrition and Enhanced Sports Performance: Muscle Building, Endurance, and Strength” by Debasis Bagchi, Sreejayan Nair, Chandan K. Sen
from Nutrition and Enhanced Sports Performance: Muscle Building, Endurance, and Strength
by Debasis Bagchi, Sreejayan Nair, Chandan K. Sen
Elsevier Science, 2013

Free creatine may stimulate protein synthesis and cause muscle hydration, which results in increased muscle mass and strength.

“Netter's Sports Medicine E-Book” by Christopher Madden, Margot Putukian, Eric McCarty, Craig Young
from Netter’s Sports Medicine E-Book
by Christopher Madden, Margot Putukian, et. al.
Elsevier Health Sciences, 2017

Both these effects occur because creatine associates with water as it is stored in the muscles.

“Training for Climbing: The Definitive Guide to Improving Your Performance” by Eric Horst
from Training for Climbing: The Definitive Guide to Improving Your Performance
by Eric Horst
Falcon Guides, 2008

els in blood; enhances endurance performance Creatine Increases anaerobic power, Yes High No Research supports claims, may increases strength cause diarrhea and muscle cramping, long-term effects unknown.

“Practical Applications in Sports Nutrition” by Heather Hedrick Fink, Lisa A. Burgoon, Alan E. Mikesky
from Practical Applications in Sports Nutrition
by Heather Hedrick Fink, Lisa A. Burgoon, Alan E. Mikesky
Jones and Bartlett Publishers, 2006

Alexia Lewis RD

Registered Dietitian Nutritionist and Certified Heath Coach who believes life is better with science, humor, and beautiful, delicious, healthy food.

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  • Any thoughts on Rhiannon Lovelace? As far as feats of strength, she has the strongwoman u64kg deadlift record(suit+straps) around 272 kg, she is shooting for 300 kg!! Check her out if you havent, she owns a gym Kaos Strength in the UK.

  • BP!!! What you think about using melatonin 5mg pre-workout?? That really boost GH levels during and pos workout and lowering oxidative stress and muscle inflammation during workouts?

  • Good vid. Thinking Im gonna try a bottle of this. I like the intense stuff but not really a fan of the beta-alanine tingles. Guess we will see

  • This dude does it right. Short and sweet and to the point. Unlike many others on YT that want to be blabbering heads. Two thumbs up for this guy.

  • 53:33 no it isn’t wtf? Anabolics/performance enhancements are really frowned upon in Europe these days. The Rocky movie is not an accurate depiction

  • Thanks. I took for some time creatine but my blood levels went through the roof it took several months to level them down to a healthily level. Any other supplement similar to creatine you would recommend?

  • Multi minerals(iron free for men unless deficient). Multi vitamins are piss poor(most at least) at providing adequate or any minerals. They up there as one of the most unsung/underutilized  best anabolic/recovery supplements. Most are deficient. Minerals among the multitude of benefits they have help vitamins work.I use the Vitamin Shoppe brand. Magnesium, Calcium, Zinc etc etc etc etc. Bodyknowledge77 approved.

  • Ben what digestive supplements do you take specifically? Poor digestion is a big factor thats been holding me back. Ive tried enzymes in the past and probiotics and still get bloated/gassy/fatigued. What do brands do you recommend?

  • Ha I used to take electro lights in my water before powerlifting workouts, but lately I’ve stopped and I’ve been feeling slightly off. I really appreciate the knowledge in these videos.

  • you should do one on SARMs I see a lot of people taking these things, they LITERALLY have no idea what they’re putting in their bodies you think these companies producing them underground are putting in what they say they are? Research and testing these compounds has already debunked they’re filled with volatile chemicals and hormones.

  • Dont consider anabolics until you are advanced lifter in your 30s-40s and has 10 years of prior lifting experience and have a clean diet and still dont see results. And consider something like TRT which may be safer and prescribed by a doctor. If your physique is that important to you, do them. And dont do a giant dose.

  • These four guys are the real deal. Thanks for the conversationthe antidote to those naive kids who might, otherwise, follow the Rich Pianas of the world.

  • Almost during the entire video the guy in the smith machine in the back just stands underneath and around the bar. Not once did he lift it up, and right at the end of the video it looks like he gets out from under the bar.:/

  • Dr Mike isratel:they take shit for fuckerry!��
    I woke up early at 4:30am and watched the entire thing, I have to get to work at 7:30. This was great, I really appreciate it.

  • Sounds like KANGEN water takes care of a lot of that, check it out ALKALINE, ANTI-OXIDANT, MICRO CLUSTERED water it’s amaizing

  • I’m assuming you’re telling people to take creatine pre/post workout because of the increased blood flow during the exercise? Creatine is more of a ”constant” supplement, where saturation is much more important than timing, unless I’m mistaken. I take my two servings every 12 hours which tends to be pre-workout and before sleep. 

  • been using Mr. Hyde on and off for a few years. i used to take half a scoop of this and a full scoop of Dr. Jekyll for great energy and pumps…would not recommend it to anyone though. There was a few occasions where i thought i was actually gunna die lol

  • Any thoughts on really long term (years) of regularly training to failure? Not sure if you can draw conclusions from that study or comment on experience. Also, please consider bringing Greg back next podcast.

  • I wouldn’t call something that shuts down your own test production “innocuous”, it implies bad advice.

    Much less chance of a freak accident with creatine.

  • You are the only one who i look forward to his videos on YouTube. Clear, honest and informative. We wanna see you winning the Arnold Classic next year..Conditioning on 2013 was great and I’m sure on 2015 will be amazing.

  • “Your morals are your morals, and my morals are my morals.  Who am I to judge you and who are you to judge me.” Louie Simmons

    My thoughts, there’s a lot of fear mongering about it.

  • John’s first cycle is EXACTLY how we did it back then.. ONLY PRECONTEST, LOW DOSED AND NO TEST BASE.. and GUARANTEE many top pro’s have done the same thing

  • I know this came out way back in February, but bruh I’ve been wanting to see somebody put John Meadows and Mike Israetel in a (digital) room together for ages. What a dream interview setup you have here. Thank you! Throwing Eric into the mix makes it even better. Hitting every angle of the conversation. Good to see John getting in there with the science-based big names.

  • Eric, can you elaborate on the communities that have a hard time believing that a 500lb squat or >315lb bench? I’ve never come across these and would be interested in learning more about why they believe what they believe.

  • 1:06:51 That was cathartic. The two things that get me irrationally annoyed are 1. the mentioned correlation!= causation and when people say that something tells you NOTHING AT ALL based on an arbitrarily decided “small sample size” regardless of the study. Those are the two tropes that people who don’t know and don’t care about science just throw out there to dismiss something they don’t like.

    When a gym acquaintance tells me “yeah but these studies on training have such a small sample size, they tell us nothing at all”. You goddamn idiot, do you actually think that when you take 30 males between 20 and 25 years old who bench their bodyweight that your physiology is completely different when you’re literally of the same age, gender and strength level?

  • I’ve been waiting to hear someone (credible) explain the likely consequences of gear in detail like Mike for 17 years. Finally. Thanks.

  • Doesn’t matter when you take Creatine. It works by chronic loading your muscles, not acute effect. Just take it once or twice daily, and if you believe the opportunity window, take it after your training session.

  • All the bullshitting you promised to skip…you actually you took 1.5 mins. To say you werent gonna do it. Lol just saying. I watched it all though.

  • Guys. you really working hard to get Ig noble price for those studies on risk injury. Folks who reported injury(prior physical limitation) before study where injured further down the line. Genius

  • Can’t say how much I appreciate this podcast such open truth really does allow me to make a conscious decision about my lifting career

  • John talks as if one should go as far as possible before taking gear like he did. Although he admitted to taking winstrol at age of 19…

    Typical gear users are so contradictory. They all say the same thing. “yeah I started using gear at 16… But I’d never recommend anyone else do so”

  • I thought it didn’t matter matter when u took creatine as long as u take it? Would it be better to take before and after workout, and still take 5g on rest days?

  • “Temporary host, Greg Nuckols”

    He seems like a permanent host by the way things are going. He should be anyways. The guy’s very knowledgeable

  • You just reminded me I should start taking creatine again. With the transition to college, I slacked off a bit and wasn’t consistent with working out. This entire summer, I have been back in the gym consistently regaining progress I made when I was in high school.

  • I think Gregg should not have backed off a bit from his premise that people having trained for many years need to go to failure AND BEYOND. In Greggs video training he said that! and I agree. I’m 66 and must do this for results. Mike is defending his premise that you don’t need to much or at the least very little. Gregg was trying to not have conflict. If Gregg was like he is in his video, he would have said, “in my opinion Mike that is bullshit. Advanced trainers will make little gains without failure and beyond.” This is common sense! Gregg should not have been afraid of not backing common sense and personal experience with “scientific literature”. This is what Mike needed to hear! People want to believe Mike’s method CAUSE IT’S EASIER! Good job Gregg on your no nonsense videos!!

  • let’s get real. Forget the creatine myth and talk some truth in bodybuilding. Like pre-workout peptides, GH, or post workout insulin dosing. Because my friends, those are the real IFBB tricks for muscle growth, apart from the obvious life dedication to anabolics, training, and diet.