Sceletium Tortuosum – Improve Cognitive Function Beat the Blues


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Sceletium tortuosum has been used for hundreds of years by South Africans to improve mood and cope with stressful situations. In fact, some accounts state that small doses of the herb mixed with a teaspoon of breast milk have been used in rural areas as a remedy for children battling cholic – interestingly enough, this practice still takes. Find out how sceletium tortuosum helps to improve your brain function, focus, clarity, and beat off the blues.

Sceletium tortuosum is a succulent plant commonly found in South Africa, which is also known as Kanna, Channa, Kougoed (Kauwgoed/ ‘kougoed’, prepared from ‘fermenting’ S. tortuosum)—which literally means, ‘chew(able) things’ or ‘something to chew’.. The generally recognised eight Sceletium species are S. crassicaule, S. emarcidum, S. exalatum, S. expansum, S. rigidum, S. strictum, S. Sceletium Tortuosum – Improve Cognitive Function & Beat the Blues Bryn Hunter 2019-06-18T14:30:40-04:00 Sceletium, potent mood booster Among the many thousands of plants used medicinally around the world, about a hundred or so are mind and mood-modifying. Sceletium tortuosum, or Kanna, is a hardy plant native to South Africa which has been used by the San people for ages to improve mood. It activates a group of alkaloids (mesembrine, mesembrenol and turtuosamine) which interact with receptors in the brain to enhance the production of dopamine and prolongs the activity of serotonin – leaving you feeling alert and happy.

Sceletium Tortuosum is a medicinal plant from South Africa. It’s also a succulent commonly known as Kanna, Channa, and Kougoed. Kanna is a herb considered by many as the king of mood support remedies. Kanna (literally meaning “something to chew”) is.

Sceletium has shocked researchers with its remarkable ability to brighten mood, dissolve tension and enhance cognitive function—all within as little as 30 minutes! [8,9] What I like most about sceletium is that it is not a stimulant. It has virtually no known side effects or interactions, and it’s not habit forming.*. Dose: 25mg and 50mg of 2:1 Sceletium extract. Conclusion: The overall results support the use of Zembrin® as a functional food with potential to improve mental health and enhance well-being with respect to cognitive function, anxiety, stress and mood.

Mucuna 10:1 extract (40% L-dopa), 200 m. The endemic South African succulent plant Sceletium tortuosum (L.) N.E. Br., family Mesembryathemaceae, is known as kanna in Nama, kougoed in Afrikaans, and sceletium in English.

Sceletium tortuosum contains mesembrine and the related alkaloids mesembranol and mesembranone. Mesembrine is known for its effects on the central nervous system. The compounds also act as serotonin-uptake inhibitors, and in specified doses act as anti-depressants, minor tranquilizers and anxiolytics used in the treatment of mild to moderate depression, psychological and psychiatric disorders.

List of related literature:

Consistently with the hypothesis that music stimulation may enhance cognitive functions by promoting brain connectivity, Schlaug and colleagues (Schlaug, Marchina, & Norton, 2009) showed increased number of fibers and volume of the arcuate fasciculus comparing patients’ brain preand post-MIT treatment.

“The Oxford Handbook of Music and the Brain” by Michael H. Thaut, Donald A. Hodges
from The Oxford Handbook of Music and the Brain
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Both Beating the Blues and Fearfighter have been approved by the UK National Institute for Health and Clinical Excellence (NICE 2006) as effective treatments.

“An Introduction To Counselling” by John McLeod
from An Introduction To Counselling
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Recent studies using instrumental conditioning techniques indicate that CB1 receptors play a role in the transition from action-outcome to stimulus-response (habit) learning.58,64,72 Thus the endocannabinoid system may play an important role in reinforcement-based instrumental learning.

“Addiction Medicine E-Book: Science and Practice” by Bankole Johnson
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Byrne JH, Zwartjes R, Homayouni R, Critz S, Eskin A. Roles of second messenger pathways in neuronal plasticity and in learning and memory: insights gained from Aplysia, in: Nairn AC, Shenolikar S, Eds.

“Essential Medical Physiology” by Leonard R. Johnson
from Essential Medical Physiology
by Leonard R. Johnson
Elsevier Science, 2003

In an experimental design, young men with less fitness, matched with regard to trait anxiety, experienced decreased anxiety immediately after 20 minutes of light intensity cycling but an increase in anxiety after hard intensity cycling (Tieman, Peacock, Cureton, & Dishman, 2002).

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Bothhad a mail­order business selling blues, rhythm and blues,and gospel music, andmail ordersindicate that WLAC’s programs of rhythm andblues and gospel music reached listeners asfar asCanada, Mexico,the Caribbean, North Africa, andother international regions via shortwave radio.

“African American Music: An Introduction” by Mellonee V. Burnim, Portia K. Maultsby
from African American Music: An Introduction
by Mellonee V. Burnim, Portia K. Maultsby
Taylor & Francis, 2014

NICE has approved a computerized CBT programme, ‘Beating the Blues’, for mild to moderate depression, suitable for those with no computer experience.

“Practical General Practice: Guidelines for Effective Clinical Management” by Alex Khot, Andrew Polmear
from Practical General Practice: Guidelines for Effective Clinical Management
by Alex Khot, Andrew Polmear
Elsevier Health Sciences, 2011

In the Gitlin et al. (2003) review, eight studies involved some form of auditory stimulation (e.g., soothing music, natural sounds, or white noise), and three studies evaluated music in combination with other sensory-based strategies.

“Dementia: Person-Centered Assessment and Intervention” by Ellen Hickey, Michelle S. Bourgeois
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Computer programs such as Beating the Blues cognitive behavioral therapy (CBT) skills have also been

“Advanced Practice Psychiatric Nursing: Integrating Psychotherapy, Psychopharmacology, and Complementary and Alternative Approaches” by Joyce J. Fitzpatrick, PhD, MBA, RN, FAAN
from Advanced Practice Psychiatric Nursing: Integrating Psychotherapy, Psychopharmacology, and Complementary and Alternative Approaches
by Joyce J. Fitzpatrick, PhD, MBA, RN, FAAN
Springer Publishing Company, 2012

6 Music integrates affective and cognitive processes in EF training and, finally, adds emotion and motivation to keep the person on task (Thaut, 2005).

“Handbook of Neurologic Music Therapy” by Michael H. Thaut, Volker Hoemberg
from Handbook of Neurologic Music Therapy
by Michael H. Thaut, Volker Hoemberg
OUP Oxford, 2014

Alexia Lewis RD

Registered Dietitian Nutritionist and Certified Heath Coach who believes life is better with science, humor, and beautiful, delicious, healthy food.

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  • I’ve always liked the strength/athlete build over the bloated bodybuilder look. It’s both aesthetically pleasing and functional. Best or both worlds. That’s what I like about the old school bodybuilders they trained for both strength and aesthetics.

  • Hey cool review. i just started my first English channel! I also reviewed c4 just now:) if you can give me any tips that would be awesome ❤❤

  • I was interested but the sour flavor was discouraging but then the sea that sherbet come in at the end made me want to try this. ����

  • was wondering if you tried the prework out mix yet, running low on my current stuff and thinking about giving man sports blend a try

  • I’m loving it. Great mental focus. It’s mid summer and I train in my garage in the heat. It’s helped me get through some crazy difficult training sessions thanks MPMD!

  • Can you make a video on peptides? GHRP-6, GHRP-2 and how they compare to HGH, and testosterone in terms of how they improve your muscle mass and how effective they are.

  • Guys just imagine if ronnie Coleman didn’t train only for bodybuilding and he also trained for powerlifting. He was training with 200lbs dumbell 12 reps so his 1 rep max was between 240/260 for sur so if he trained for power he would do 300 easy

  • For having such huge shoulders and traps, I’m always surprised how small this dudes neck is. No hate, I have the same problem, I’m just not insanely muscular. Maybe it’s just a weak point we both share?

  • No other pre-workout would attempt to give such a breakdown. 1st because their products wouldn’t compare & 2nd they don’t understand the biology and effects at Derek’s level.
    CONVINCED. Have learned so much watching these posts. ORDERED 3 bottles.
    Thanks for your research and the terrific explanation of why we need the ingredients and in what dosages.

  • Tried it last night, great formulation 10/10 pump 8/10 energy. Great replacement of the vasoconstructive 1,3 and dmha pre workouts also 1 scoop would be great for night workouts with half the caffeine.

  • Going to cop both mode and nitric. I saw both videos, you did convince me 100%. I always stack with decent preworkouts such as nitraflex, esp, fury, and mega pre. They’re good pres but definitely looking forward for your pres.

  • Love your content Derek. I wish I could afford to have you dial in a meal and workout plan. Just ordered gorilla mode super excited!!

  • Hey Derrick! I’m looking for an old video for a mk-677 and cjc protocol. That raises GH equivalent to large doses of growth. If ya can help me find this I would appreciate it.
    Keep up the great content man!
    Most informative Chanel for this genre!!!

  • My only recommendation for the next iteration of this is adding Theanine to mitigate the overstimulation by the high amount of caffeine. Any comment on why you didn’t include it? Seems like a no-brainer to me. Great stuff tho!

  • Why would a strongman use anadrol if it kills your appetite?
    Also, does anyone use turinabol for anything?
    Waiting impatiently for the Mike Tyson video.

  • So cool to see/hear this from your perspective! Everyone at the office is big fans of your videos, honored to have you try them out!

    MOST OF THESE PRODUCTS HAVE 1% 2% creatine (DE MINIMIS) IDK WHY BUT PPL ON creatine GET VERY DEFENSIVE WHEN YOU TELL THEM EXACTLY WHAT creatine IS (fake muscle capturing water weight to give ‘BIG’ fake look) THEY GET VERY DEFENSIVE

  • T, As I listened to the intro disclaimer I kinda got a laugh. I remember a similar disclaimer in your earlier videos regarding firearms. You know I like to predict things so I am going way out on a limb with this one. Dr. Talon Sei

  • Should I have any health concerns with taking 350 mg of N-Phenethyl Dimethylamine Citrate, especially combined with that caffeine. I’ve read that maximum recommend daily dose is only 200mg

  • As thorough and elaborate this man is with his content, I’m absolutely going to give it a try. Keep up the kick ass content bro ����

  • What to know if youve noticed any afternoon crashes when taking the Brain Bridge in the AM? I typically have a cup of coffee in the morning but by 2 in the afternoon I’m dragging.

  • First video i watched of yours was your edc video the first one i think it was you sitting on a stump. Then i forgot about your channel and the name was hard to figure out but i found your channel again so now i’m watching your stuff again.

  • Damn bro. Wish you would have been around as a resource when i was younger. I certainly appreciate it now, but man it wouldve saved me a lot of bullshit. Your honesty and willingness to share your own decisions is what seperates you literally from anyone putting out quality, science based content right now. Awesome stuff. Just ordered Gorilla Mode for first time, looking forward to the results.

  • You said two servings but also that each serving is 350mg of caffeine. But according to the FDA 400mg is the max amount of caffeine you should consume a day to avoid caffeine poisoning.

  • Best pre-workout I’ve ever used
    Didn’t make me anxious n’ shit
    One of the best training sessions I’ve had in a long time
    Thanks man From here on out I’m a returning customer

  • I need your advice with a bad bad trying not to have surgery but on medication blood ores,pain so I wont get surgery but there enough there my question after u tried it I need the replacement that parmicudical are talk from me here it is do u suggest it to me hopefully a benefit I know there’s more guys out the that got injured hammered in construction this could be good Tai think about as u us alot of us I am sure need to

  • Hello my friend I liked jaket and I can not buy it from my country. I do not have a Visa card. Can you send it to me as a gift? I live in Tunisia.

  • With respect to the glycerol clumping dilema, is it the moisture that is the number one reason for the binding or is due to the interaction with other ingredients. I always keep some extra silica pouches on hand because the house can get really humid in the somertime. Some silica can be microwaved to remove the moisture to start fresh, however I am not sure that the pouch that holds the silica makes it possible. The pre workout that you are discussing seems to be going above and beyond what the expectation for a pre workout should be. In some cases there are several ingredients that one should take regardless if you exercise or not. I wish that in someway the packaging in the future could resemble tide packets meaning pre measures and packaged dosing or better yet tablets similiar to alka seltzer..this would arguably remove the concern for clumping…

  • Talon, I’m looking to get my first firearm, mainly for conceal, but also something fun to shoot down range. Thinking about either the M&P 2.0 Compact or the Shield. What’s your opinion?

  • My guy, you’re one of the most real people on this platform and we all appreciate it. Articulate, informative, and you’re a chill ass dude. If I saw you on the street I’d 10/10 get you a beer

  • So I got my package in the mail today and took two scoops right off the rip and trained back. Had lots of steady smooth energy with none of the “weird” feelings you get from other pre workouts. I’m not even talking about the tingles you get. I’m talking about that other weird feeling that’s hard to describe. Almost like you don’t want people to look you I the eyes when you’re talking to them and the uneasy feeling once you’re done with your workout. None of that. The whole workout was almost like one long superset and I had more energy still once I got home and cleaned up all the leaves in my yard. Pump was pretty good too. I’m gonna do biceps in my basement tomorrow and see how pumped I get for that. Halfway through my back workout I get this slight euphoric feeling. Nothing crazy, but just in an overall good mood and energetic. I was super focused towards the end of my workout when the pump got better and better. I put my hand on my lats while doing one arm pull downs and I could feel the muscle stretch and contract and it felt like I could feel the blood pumping through the muscle. Very good mind muscle connection with this product. No shakes. no jitters. Just clean smooth focused energy

  • Awesome video thanks for the info been thinking about taking a supplement like brain bridge tried a weeks sample of mastermind and I liked it might try this instead. Once again great content keep it coming.

  • This pre-workout is absolutely INCREDIBLE! I train full body, and have done two workouts with it this far. At the end of my workout I felt that I could do it all over again. Zero jitters, zero crash, euphoria, laser focus, power, pump, intensity. Here’s the kickerI’ve been using 1scoop. Do yourself a massive favor and grab a tub. You’ll never want to go without it again.

  • Man some gym vids would be awesome. I’ve been hitting it hard at the gym for last month and to hear that you’ve been getting into it is awesome.

  • Took 2 scoops around 630 last night felt good during workout. After workout heart rate was high anywhere from 115 to 130 for about 7 hrs after. Also body feel hot still and it’s now been 12 hrs. Heart rate is lower around 105 my normal resting is 75.

  • Hey bro don’t know why but this video is one of your best videos and that’s weird because I mainly just like your gun videos. But anyways keep up the good work man

  • Hey Derek, you would you ever consider getting in a supplier in Australia? Would love to buy some but the cost plus shipping on your ebay site is super expensive.

  • Got Gorilla Mode today… it’s the truth. By far the best pre I’ve used. I actually save money on this because now I don’t have to buy extra Citrulline, or Creatine. Its also one of the very few PWOs with N-Phenethyl Dimethylamine. And, it tastes OK..which impressive considering everything that’s in it.

  • 6:46 Always hilarious to see how some of these enhanced ”athletes” are just walking pharmacies! ������
    PED athletes: just remember to stay humble, you’re not better than natural athletes, don’t brag thinking you deserve more fame or glorification than athletes solely relying on their own sheer will, work ethic, discipline, determination and most importantly their own 2 testicules! ����

  • Great video as always. Big fan of the channel… You have definitely scooped me on some things with your reviews. Keep up the great work!!!

  • Very interested in trying this product. Only question is don’t creatine and betaine also need to be taken every day, much like beta alanine, to see effects? That seemed like one of the main reason you kept beta alanine out of the product.

  • well, I never took the time to find out about “steroids”, thanks for the information! good for you for taking the time to research and lear all this

  • Awesome video man. I have a question when you didn’t get the brain bridge did you feel the urge to get it, like when you don’t get your coffee you are not in the mood for anything? I’m like you didn’t take any kind of nootropics but eager to know more.

  • Down here to satisfy the algorithm. Also, don’t think I’ve ever commented before. But been loving the content for quite some time now. Keep it up man!

  • Has anyone here ran trenbolen and Dianabol together with testosterone as a base? Let me know please, and the affect and negative effect, thank you!

  • It’s me again. Got my order Saturday. THIS SHIT IS AMAZING!!! The pumps are sick, the veins are popping out, the focus is epic. EXCELLENT PRODUCT!!! 10/10

  • Just viewing this video now, tbh I always cringe when I see someone review a product but I most say Derek is for the people not for the profit and I’m defs going to support him even tho I’m not in the states and I will get fucked but a man this honest deserves support
    Edit: shitttttt this guy even got us covered outside the us with eBay. My nigga

  • I’d love to try your products but the shipping + duties are prohibitive in europe. I hope that changes in the future, however I understand that it might not be fisible yet.

  • Dude alpha brain changed everything for me. I thought i was forgetting everything because i was ingesting too much youtube and research. The problem was i wasnt taking care of my brain. Onit obviously makes good stuff especially alpha brain

  • One of the things with caffeine, and products that promote “energy” increase, productivity and contains acids, you need to intake more water than normal. This is due to the fact that caffeines and acids naturally tend to decrease ph levels in your body you need to create a balance with your ph in your body. Try to compensate your intake of the brain bridge with extra water throughout the day to keep your hydration at an equilibrium/ and or make your ph as base as possible. I want to try to take this stuff eventually, I’m currently at CSSM medical school and super into the body and its functions. Its awesome.

  • Just ordered this and the stimulant free version, planning on taking one scoop of each. Is there any difference in the two besides the amount of caffeine?

  • Let me tell y’all about mike tyson i grew up with mike i first met mike i was 8 years old he was 7 years old and at 7 u can c the muscles of his arms chest delts legs all over at the time my farther was a local bodybuilder he was about 6ft 190 pounds ripped and he and my was play fighting and he punch my farther in the stomach and he knock the wind out of him

  • Do people find dbol or anadrol effective as a preworkout or find something lime caffeine/ephedrine more effective as a pre workout.

  • Just received and tried it today. I’ve only bought a pre-workout once before, otherwise I’ve been making my own PW for the last 3 months.

    I did 1 scoop with good results:
    Pump was nice (7/10)
    Stimulation wasn’t anything crazy, no crash (6/10)
    Clear-headed energy and focus was awesome (10/10)
    Taste: I was surprised it tasted very nice (9/10)

    Some background: I put 10g L-citrulline in my own pre workout, so 1 scoop didn’t quite get the pump I’m used to. 2 scoops will for sure though. Also I love a high stim pre workoutI put 150-200 mg DMHA and 200-400 mg caffeine in mine (not all the time). So that’s why the stimulation with 1 scoop was very impressive.

    Will try 2 scoops tomorrow and update. So far I’m impressed and I’m guessing 2 scoops will be 10/10!

  • Idk if you still do this kind of stuff but you should do a natty or not video on Eric Bugenhagen. Guy has a fantastic physique as well as strength and is am inspiration to many naturals. Would be an interesting watch

  • Do you need to take l-citrulline multiple times per day to get the cardiovascular benefits? As always, thanks for the great info!

  • Hey bro.Really glad that you put it all in one video and not just check in every week.
    Long video,but didn’t feel that way. Hope you keep working out. Just go for lean muscle mass, it suits your body type.
    Keep up the good work!

  • I agree with what you said about the creatine and how companies cheap out by not putting the full dose. But in all honesty, it doesn’t really matter because most people aren’t taking a pre-workout every single day and you need to take creatine every single day. So at the end of the day you’re going to have to get it from another source anyway.

  • The bottle is a shakercup, you put water and the c4 thing in that and then shake it:D lol:D But it’s probably like GFUEL?:D Love all the reviews, keep up the good work!

  • I want to support you, but it seems that I can’t ship your pre workouts to my place. I’m in Winnipeg, MB, Canada. Anything I can do?

  • Strength is not a bi product of muscle size. There are guys who look like fn sticks walking around, some powerlifters who look like they dont even lift but can squat 700 pounds bench 400 and deadlift 600. There is no correlation in muscle size equalling strength. Genetics, type of muscle fibers you have genetically play a role. Def the way you work out too, a lot of variables involved, but muscle size dies not equal strength all the time.

  • I just asked people on forums why 500mg test/week is recommended as a base instead of for example 200mg and their answer is that low test is bad for gains. I tell them that men produce less than 100mg/week test naturally which makes 200mg test a high dose of test and people tell me that I’m trying to reinvent the wheel and should just accept the 500mg test as the best dose.

  • I’ve been looking into keto and fasting recently and I was wondering would Gorillamode break a fast? Just wanna know to better plan my workout schedule when I get this (since the video convinved me to try it)

  • The fact that you did so much research and are so knowledgeable is really unique in this industry. I’ll definitely be buying this product

  • Just bought one for the 1st time, downed it, and now my hands are itching like crazy! Is that the “tingle” they mention on the can?

  • Derek you should do crossfit cycles next. Also an interesing but possibly controversial topic would be military athlete steroid cycles (specifically members in the SpecOps/JSOC community).

  • I purchased a tub and have to disagree with him on its taste. We’ve all consumed all manner of powders and chemicals in our supplements and given the crazy number of them in this, you’d expect it to taste terrible, like he says.

    But honestly tho, It tastes very pleasant. The creators did a fantastic job coming up with a flavor here. I really like it. It’s just a swig anyway and the flavor makes consuming it squarely on the enjoyable side as opposed to just something you bear swallowing.

    You can tell he really cares about the utmost quality of his product thru this vid and his criticism of the taste because yeah, the taste is perfectly fine.

    Based on the taste alone, it should be called Kitten’s Kool-Aid instead.

  • Hey everyone, I hope you enjoy this extra long upload of the 30 days of testing Brain Bridge. I know there will be a lot of questions on the topic so if you want to see my answers and thoughts check out the info in the description!

  • Ibogaine was the singal most spiritual experience of my life. Proved to me without a shadow of doubt there is more to life than what meets the eye. Each vision i had seemed more real than this life. I was conciousnesly aware navigating my visions and once i understood the vision it would immediately disapear and i would enter a new vision/ realm with a new lesson to learn. There are no words to describe this other than magic, there truly is a spirit world around and within us all. Thanks for covering this! Cheers!